Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest (Q22254227)

Mitogen-activated protein kinase kinase 6

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

regulation of cell cycle

0 references

Y Wang

7

Y

Wang

1 reference

7 February 2023

X Wang

1

X

Wang

1 reference

7 February 2023

C H McGowan

2

C H

McGowan

1 reference

7 February 2023

M Zhao

3

M

Zhao

1 reference

7 February 2023

L He

4

L

He

1 reference

7 February 2023

J S Downey

5

J S

Downey

1 reference

7 February 2023

C Fearns

6

C

Fearns

1 reference

7 February 2023

S Huang

8

S

Huang

1 reference

7 February 2023

J Han

9

J

Molecular and Cellular Biology

Han

1 reference

7 February 2023

language of work or name

English

0 references

publication date

July 2000

0 references

published in

0 references

volume

20

0 references

issue

13

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page(s)

4543-52

0 references

cites work

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Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

19 March 2017

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Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

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19 March 2017

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

19 March 2017

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Cell cycle regulation of human WEE1

19 March 2017

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19 March 2017

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Caffeine inhibits the checkpoint kinase ATM

19 March 2017

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19 March 2017

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Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

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RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis

19 March 2017

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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

19 March 2017

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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

19 March 2017

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

19 March 2017

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Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells

19 March 2017

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

19 March 2017

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7 April 2017

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Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1

27 September 2017

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Explaining differences in sensitivity to killing by ionizing radiation between human lymphoid cell lines

27 September 2017

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27 September 2017

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MAPK inactivation is required for the G2 to M-phase transition of the first mitotic cell cycle

27 September 2017

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27 September 2017

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Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

27 September 2017

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27 September 2017

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Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells

27 September 2017

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27 September 2017

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Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

27 September 2017

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Cell cycle control and cancer chemotherapy

27 September 2017

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27 September 2017

Cdc2 regulatory factors

1 reference

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Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Mechanism by which caffeine potentiates lethality of nitrogen mustard

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates

27 September 2017

1 reference

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The cdc25 M-phase inducer: an unconventional protein phosphatase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Effects of ionizing- and UV B-radiation on proteins controlling cell cycle progression in human cells: comparison of the MCF-7 adenocarcinoma and the SCL-2 squamous cell carcinoma cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

The genetic defect in ataxia-telangiectasia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Mitogen-activated protein kinase kinase 2 activation is essential for progression through the G2/M checkpoint arrest in cells exposed to ionizing radiation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

A link between MAP kinase and p34(cdc2)/cyclin B during oocyte maturation: p90(rsk) phosphorylates and inactivates the p34(cdc2) inhibitory kinase Myt1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Checkpoint pathways come of age.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

The primary structure of p38 gamma: a new member of p38 group of MAP kinases

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Heterogeneity of radiation response of a parent human epidermoid carcinoma cell line and four clones

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Inhibition of p34cdc2 kinase activity by etoposide or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

The p38 MAP kinase pathway and its biological function

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

A kinase from fission yeast responsible for blocking mitosis in S phase.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85840

Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10848581

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6b

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10848581

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10848581