Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway (Q22253244)

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English	Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway	scientific article

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scholarly article

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Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway (English)

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coagulation factor II thrombin receptor

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GOA release 2020-03-11

Coagulation factor II, thrombin

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GOA release 2020-03-11

Signal transducer and activator of transcription 1

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GOA release 2020-03-11

Signal transducer and activator of transcription 1

1 reference

GOA release 2020-03-11

author name string

Y Q Huang

1

author given names

Y Q

author last names

Huang

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7 February 2023

J J Li

2

author given names

J J

author last names

Li

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7 February 2023

S Karpatkin

3

author given names

S

author last names

Karpatkin

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7 February 2023

language of work or name

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publication date

3 March 2000

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Journal of Biological Chemistry

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275

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6462-8

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9

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Cyclins and cancer

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Mammalian G1 cyclins

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

p21 is a universal inhibitor of cyclin kinases

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Cellular consequences of thrombin-receptor activation

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor

1 reference

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21 January 2018

Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: a mechanism for stabilizing neutrophil adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Protease-activated receptor 3 is a second thrombin receptor in humans

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

A dual thrombin receptor system for platelet activation

1 reference

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21 January 2018

The cloned thrombin receptor is necessary and sufficient for activation of mitogen-activated protein kinase and mitogenesis in mouse lung fibroblasts. Loss of responses in fibroblasts from receptor knockout mice

1 reference

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21 January 2018

Thrombin receptor activation elicits rapid protein tyrosine phosphorylation and stimulation of the raf-1/MAP kinase pathway preceding delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for an obligate autocrine mechanism promot

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Peptide growth factors are multifunctional

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Ligand cross-reactivity within the protease-activated receptor family.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Molecular mechanisms of angiotensin II in modulating cardiac function: intracardiac effects and signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Thrombin receptor activating mutations. Alteration of an extracellular agonist recognition domain causes constitutive signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

21 January 2018

Thrombin stimulates melanoma tumor-cell binding to endothelial cells and subendothelial matrix

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of JAK2 in thrombin-stimulated human platelets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

7 January 2021

based on heuristic

inferred from DOI database lookup

STATs and cytokine specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

7 January 2021

based on heuristic

inferred from DOI database lookup

The seven-transmembrane-spanning receptors for endothelin and thrombin cause proliferation of airway smooth muscle cells and activation of the extracellular regulated kinase and c-Jun NH2-terminal kinase groups of mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

7 January 2021

based on heuristic

inferred from DOI database lookup

Thrombin-induced mitogenesis of vascular SMC is partially mediated by autocrine production of PDGF-AA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

7 January 2021

based on heuristic

inferred from DOI database lookup

Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6462

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.275.9.6462

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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