Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration (Q22241965)

AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

31P NMR Bayesian spectral analysis of rat brain in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

AMPK alterations in cardiac physiology and pathology: enemy or ally?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

The relationship between AMP-activated protein kinase activity and AMP concentration in the isolated perfused rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Hypoxia and AMP independently regulate AMP-activated protein kinase activity in heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Regulation of glucose transport by the AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Insulin-independent pathways mediating glucose uptake in hindlimb-suspended skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Single-sample preparation for simultaneous cellular redox and energy state determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Long-term metformin treatment stimulates cardiomyocyte glucose transport through an AMP-activated protein kinase-dependent reduction in GLUT4 endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Relationship between 5-aminoimidazole-4-carboxamide-ribotide and AMP-activated protein kinase activity in the perfused mouse heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Role of AMP-activated protein kinase in mechanism of metformin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

The Effect of AMP-Activated Protein Kinase and Its Activator AICAR on the Metabolism of Human Umbilical Vein Endothelial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

Model systems for modulating the free energy of ATP hydrolysis in normoxically perfused rat hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

7 January 2021

Adenosine production and energy metabolism in ischaemic and metabolically stimulated rat heart

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

7 January 2021

Mechanisms of hypoxic coronary vasodilatation in isolated perfused rat hearts

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

7 January 2021

NMR-invisible ATP in heart: fact or fiction?

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

7 January 2021

Acute antihyperglycemic mechanisms of metformin in NIDDM. Evidence for suppression of lipid oxidation and hepatic glucose production

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00002.2007

7 January 2021