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Protein tyrosine phosphatase, receptor type, C (Q21985631)

From Wikidata
mammalian protein found in Mus musculus
  • Ly-5
  • Ptprc
  • lymphocyte antigen 5
  • receptor-type tyrosine-protein phosphatase C
  • L-CA
  • T200
  • lymphocyte common antigen
  • leukocyte common antigen
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    English
    Protein tyrosine phosphatase, receptor type, C
    mammalian protein found in Mus musculus
    • Ly-5
    • Ptprc
    • lymphocyte antigen 5
    • receptor-type tyrosine-protein phosphatase C
    • L-CA
    • T200
    • lymphocyte common antigen
    • leukocyte common antigen

    Statements

    molecular function
    protein tyrosine phosphatase activity
    determination method or standard
    IDA
    ISS
    IEA
    ISO
    8 references
    retrieved
    16 July 2018
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P06800
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    ISS
    retrieved
    16 July 2018
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    ISO
    retrieved
    16 July 2018
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P06800
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    16 July 2018
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    16 July 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    16 July 2018
    stated in
    Involvement of CD45 in adhesion and suppression of apoptosis of mouse malignant T-lymphoma cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    16 July 2018
    stated in
    Detection of restricted isoform expression and tyrosine phosphatase activity of CD45 in murine dendritic cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    16 July 2018
    stated in
    Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    protein tyrosine phosphatase activity
    determination method or standard
    IDA
    IEA
    IGI
    ISO
    ISS
    9 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P06800
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    ISS
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P06800
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Involvement of CD45 in adhesion and suppression of apoptosis of mouse malignant T-lymphoma cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Detection of restricted isoform expression and tyrosine phosphatase activity of CD45 in murine dendritic cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    protein tyrosine phosphatase activity
    determination method or standard
    IBA
    IDA
    IEA
    IGI
    ISO
    ISS
    10 references
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P06800
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    ISS
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    ISO
    retrieved
    9 May 2019
    stated in
    CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IGI
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P06800
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Detection of restricted isoform expression and tyrosine phosphatase activity of CD45 in murine dendritic cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Involvement of CD45 in adhesion and suppression of apoptosis of mouse malignant T-lymphoma cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IBA
    cell component
    external side of plasma membrane
    determination method or standard
    IDA
    ISO
    44 references
    retrieved
    24 April 2018
    stated in
    FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    ISO
    retrieved
    24 April 2018
    stated in
    Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    GATA-3 is required for early T lineage progenitor development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin‐2‐deficient colitis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Mac-1 (CD11b/CD18) and CD45 mediate the adhesion of hematopoietic progenitor cells to stromal cell elements via recognition of stromal heparan sulfate
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Essential role for ZAP-70 in both positive and negative selection of thymocytes
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Detection of restricted isoform expression and tyrosine phosphatase activity of CD45 in murine dendritic cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Differential T cell costimulatory requirements in CD28-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Accessory protein-like is essential for IL-18-mediated signaling
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Immunological properties of murine thymus-dependent lymphocyte surface glycoproteins
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Generation of T cells with differential responses to alloantigens in CD45 exon 6-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Cholinergic chemosensory cells in the trachea regulate breathing
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Murine models of chronic lymphocytic leukaemia: role of microRNA-16 in the New Zealand Black mouse model
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Transgenic major histocompatibility complex class I antigen expressed in mouse trophoblast affects maternal immature B cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunity
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    miR-181b negatively regulates activation-induced cytidine deaminase in B cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Syk tyrosine kinase required for mouse viability and B-cell development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Dissociation of severe lupus-like disease from polyclonal B cell activation and IL 2 deficiency in C3H-lpr/lpr mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    external side of plasma membrane
    determination method or standard
    IDA
    IEA
    ISO
    44 references
    retrieved
    9 May 2019
    stated in
    FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    ISO
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Syk tyrosine kinase required for mouse viability and B-cell development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Mac-1 (CD11b/CD18) and CD45 mediate the adhesion of hematopoietic progenitor cells to stromal cell elements via recognition of stromal heparan sulfate
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Generation of T cells with differential responses to alloantigens in CD45 exon 6-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin‐2‐deficient colitis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Murine models of chronic lymphocytic leukaemia: role of microRNA-16 in the New Zealand Black mouse model
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Dissociation of severe lupus-like disease from polyclonal B cell activation and IL 2 deficiency in C3H-lpr/lpr mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Cholinergic chemosensory cells in the trachea regulate breathing
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Transgenic major histocompatibility complex class I antigen expressed in mouse trophoblast affects maternal immature B cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Accessory protein-like is essential for IL-18-mediated signaling
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    GATA-3 is required for early T lineage progenitor development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunity
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    miR-181b negatively regulates activation-induced cytidine deaminase in B cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Immunological properties of murine thymus-dependent lymphocyte surface glycoproteins
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Essential role for ZAP-70 in both positive and negative selection of thymocytes
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Differential T cell costimulatory requirements in CD28-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IDA
    biological process
    B cell differentiation
    determination method or standard
    IMP
    5 references
    retrieved
    9 May 2019
    stated in
    Either of the CD45RB and CD45RO isoforms are effective in restoring T cell, but not B cell, development and function in CD45-null mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    9 May 2019
    stated in
    The Motheaten Mutation Rescues B Cell Signaling and Development in CD45-deficient Mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    9 May 2019
    stated in
    CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    9 May 2019
    stated in
    Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling.
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    9 May 2019
    stated in
    Phenotypical and functional alterations in the mucosal immune system of CD45 exon 9 KO mice
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    positive regulation of B cell proliferation
    determination method or standard
    IMP
    ISO
    5 references
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    ISO
    retrieved
    24 April 2018
    stated in
    CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    24 April 2018
    stated in
    T-cell-independent antiviral B cell responses in CD45-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    24 April 2018
    stated in
    The Motheaten Mutation Rescues B Cell Signaling and Development in CD45-deficient Mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    24 April 2018
    stated in
    Differential requirements of CD45 for lymphocyte development and function
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P06800&geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    positive regulation of B cell proliferation
    determination method or standard
    IEA
    IMP
    ISO
    6 references
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    ISO
    retrieved
    9 May 2019
    stated in
    Differential requirements of CD45 for lymphocyte development and function
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    9 May 2019
    stated in
    The Motheaten Mutation Rescues B Cell Signaling and Development in CD45-deficient Mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    9 May 2019
    stated in
    T-cell-independent antiviral B cell responses in CD45-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    9 May 2019
    stated in
    CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IMP
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06800
    determination method or standard
    IEA

    Identifiers

     
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                      Retrieved from "https://www.wikidata.org/w/index.php?title=Q21985631&oldid=2023260364"