Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes (Q21245213)

18 August 2022

5

Chanson J Brumme

Chanson J

Brumme

1 reference

18 August 2022

21

Mark A Brockman

Mark A

Brockman

1 reference

18 August 2022

Guinevere Q Lee

9

Guinevere Q

Lee

1 reference

18 August 2022

Zabrina L Brumme

22

Zabrina L

Brumme

1 reference

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David R Bangsberg

David R

Bangsberg

1 reference

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Bruce D Walker

Bruce D

Walker

1 reference

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Philip J R Goulder

Philip JR

Goulder

1 reference

18 August 2022

13

Conrad Muzoora

Conrad

Muzoora

1 reference

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1

Jaclyn K

Mann

Jaclyn K Mann

1 reference

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18

P Richard

Harrigan

P Richard Harrigan

1 reference

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3

Xiaomei T

Kuang

Xiaomei T Kuang

1 reference

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6

Philip

Mwimanzi

Philip Mwimanzi

1 reference

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Saleha

Omarjee

Saleha Omarjee

1 reference

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Bemuluyigza

Baraki

Bemuluyigza Baraki

1 reference

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11

Ryan

Danroth

Ryan Danroth

1 reference

18 August 2022

Helen Byakwaga

2

Helen

Byakwaga

1 reference

18 August 2022

Anh Q Le

4

Anh Q

Le

1 reference

18 August 2022

Eric Martin

8

Eric

Martin

1 reference

18 August 2022

Rosemary McCloskey

12

Rosemary

McCloskey

1 reference

18 August 2022

Peter W Hunt

15

Peter W

Hunt

1 reference

18 August 2022

Jeff N Martin

19

Jeff N

Martin

1 reference

describes a project that uses

18 August 2022

language of work or name

English

0 references

publication date

2013

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published in

Retrovirology

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volume

10

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issue

1

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page(s)

100

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ImageQuant

object named as

ImageQuant

2 references

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3849644/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

exact match

https://scigraph.springernature.com/pub.10.1186/1742-4690-10-100

0 references

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19 March 2017

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Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

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24 March 2017

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Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix

7 April 2017

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No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial

10 May 2017

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Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants?

12 September 2017

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HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation

12 September 2017

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Immune selection in vitro reveals human immunodeficiency virus type 1 Nef sequence motifs important for its immune evasion function in vivo

12 September 2017

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Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy

12 September 2017

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Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection

12 September 2017

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Mechanisms of HIV-1 Nef function and intracellular signaling

12 September 2017

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Tracking a century of global expansion and evolution of HIV to drive understanding and to combat disease

12 September 2017

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Subtype-associated differences in HIV-1 reverse transcription affect the viral replication

12 September 2017

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Gag-protease-mediated replication capacity in HIV-1 subtype C chronic infection: associations with HLA type and clinical parameters

12 September 2017

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Impact of HIV-1 viral subtype on disease progression and response to antiretroviral therapy

12 September 2017

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HIV-1 viral subtype differences in the rate of CD4+ T-cell decline among HIV seroincident antiretroviral naive persons in Rakai district, Uganda

12 September 2017

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Phylogenetic analysis of population-based and deep sequencing data to identify coevolving sites in the nef gene of HIV-1.

12 September 2017

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HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins

12 September 2017

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CCR5- and CXCR4-tropic subtype C human immunodeficiency virus type 1 isolates have a lower level of pathogenic fitness than other dominant group M subtypes: implications for the epidemic

12 September 2017

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HIV-1 Nef: at the crossroads

12 September 2017

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HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells

12 September 2017

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Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes

12 September 2017

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The challenge of HIV-1 subtype diversity

12 September 2017

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Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1

12 September 2017

1 reference

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Impact of Nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus

12 September 2017

1 reference

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Multiple validated measures of adherence indicate high levels of adherence to generic HIV antiretroviral therapy in a resource-limited setting

12 September 2017

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Impact of clade diversity on HIV-1 virulence, antiretroviral drug sensitivity and drug resistance

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Proline 78 is crucial for human immunodeficiency virus type 1 Nef to down-regulate class I human leukocyte antigen

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Disrupting surfaces of nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Single Nef proteins from HIV type 1 subtypes C and F fail to upregulate invariant chain cell surface expression but are active for other functions.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Differential effects of primary human immunodeficiency virus type 1 nef sequences on downregulation of CD4 and MHC class I.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Attenuation of multiple Nef functions in HIV-1 elite controllers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849644

Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication.

30 May 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-10-100

Genetic and functional analysis of HIV type 1 nef gene derived from long-term nonprogressor children: association of attenuated variants with slow progression to pediatric AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-10-100

Genetic characterization of the nef gene from human immunodeficiency virus type 1 group M strains representing genetic subtypes A, B, C, E, F, G, and H.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-10-100

Preferential in-utero transmission of HIV-1 subtype C as compared to HIV-1 subtype A or D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-10-100

Dynamic range of Nef functions in chronic HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-10-100

HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 loads

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24041011

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1742-4690-10-100

0 references