NME/NM23 nucleoside diphosphate kinase 1 (Q21173771)

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mammalian protein found in Homo sapiens
  • granzyme A-activated DNase
  • epididymis secretory sperm binding protein
  • NM23-H1
  • metastasis inhibition factor nm23
  • nucleoside diphosphate kinase A
  • GAAD
  • NDP kinase A
  • tumor metastatic process-associated protein
  • NME1
  • non-metastatic cells 1, protein (NM23A) expressed in
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Language Label Description Also known as
English
NME/NM23 nucleoside diphosphate kinase 1
mammalian protein found in Homo sapiens
  • granzyme A-activated DNase
  • epididymis secretory sperm binding protein
  • NM23-H1
  • metastasis inhibition factor nm23
  • nucleoside diphosphate kinase A
  • GAAD
  • NDP kinase A
  • tumor metastatic process-associated protein
  • NME1
  • non-metastatic cells 1, protein (NM23A) expressed in

Statements

molecular function
protein binding
determination method
IPI
10 references
retrieved
8 April 2019
stated in
Interaction of the tumor metastasis suppressor nonmetastatic protein 23 homologue H1 and estrogen receptor alpha alters estrogen-responsive gene expression
GOA
curator
UniProt
UniProt protein ID
P15531
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
Evidence for interaction between human PRUNE and nm23-H1 NDPKinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
An empirical framework for binary interactome mapping
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
identical protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
Evidence for interaction between human PRUNE and nm23-H1 NDPKinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
retrieved
8 April 2019
stated in
NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15531
determination method
IPI
nucleoside diphosphate kinase activity
determination method
IEA
EXP
IDA
7 references
retrieved
26 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P15531
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
IEA
retrieved
26 September 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
IEA
retrieved
26 September 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
IEA
retrieved
26 September 2017
stated in
Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases
GOA
curator
UniProt
UniProt protein ID
P15531
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
IDA
retrieved
26 September 2017
stated in
Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
EXP
retrieved
26 September 2017
stated in
Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
EXP
retrieved
26 September 2017
stated in
Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
EXP
nucleoside diphosphate kinase activity
determination method
EXP
IBA
IDA
IEA
TAS
9 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
TAS
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P15531
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
IEA
retrieved
1 January 2018
stated in
Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases
GOA
curator
UniProt
UniProt protein ID
P15531
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
IBA
retrieved
1 January 2018
stated in
Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
EXP
retrieved
1 January 2018
stated in
Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
EXP
retrieved
1 January 2018
stated in
Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15531&geneProductId=UniProtKB:P15531
determination method
EXP
cell component
biological process

Identifiers

 
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