LSM8 homolog, U6 small nuclear RNA associated (Q21121607)

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mammalian protein found in Homo sapiens

U6 snRNA-associated Sm-like protein LSm8
N-alpha-acetyltransferase 38, NatC auxiliary subunit
MAK31-like protein
LSM8
LSM8 U6 small nuclear RNA associated

Language	Label	Description	Also known as
English	LSM8 homolog, U6 small nuclear RNA associated	mammalian protein found in Homo sapiens	U6 snRNA-associated Sm-like protein LSm8 N-alpha-acetyltransferase 38, NatC auxiliary subunit MAK31-like protein LSM8 LSM8 U6 small nuclear RNA associated

Statements

1 reference

13 November 2019

UniProt protein ID

LSM domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95777

LSM domain, eukaryotic/archaea-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Sm-like protein Lsm8 family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

5 references

8 April 2019

Dynamic protein-protein interaction wiring of the human spliceosome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

8 April 2019

Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

8 April 2019

A protein interaction framework for human mRNA degradation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

8 April 2019

Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

8 April 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

U6 snRNA binding

determination method

1 reference

8 April 2019

A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

determination method

4 references

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

31 October 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

31 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

spliceosomal complex

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

determination method

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

precatalytic spliceosome

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

U4/U6 x U5 tri-snRNP complex

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

8 April 2019

Molecular architecture of the human U4/U6.U5 tri-snRNP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

U2-type precatalytic spliceosome

determination method

1 reference

8 April 2019

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

determination method

1 reference

8 April 2019

A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

biological process

mRNA processing

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

mRNA splicing, via spliceosome

determination method

mRNA splicing, via spliceosome

determination method

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

1 January 2018

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95777&geneProductId=UniProtKB:O95777

determination method

RNA metabolic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95777

determination method

mRNA splicing, via spliceosome

determination method

LSM domain, eukaryotic/archaea-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95777

Sm-like protein Lsm8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95777

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000249299

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000249299

ENSP00000395263

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395263

ENSP00000403811

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000403811

ENSP00000408267

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000408267

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

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