splicing factor proline and glutamine rich (Q21114335)

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mammalian protein found in Homo sapiens
  • 100 kDa DNA-pairing protein
  • splicing factor, proline- and glutamine-rich
  • epididymis secretory sperm binding protein
  • SFPQ
  • polypyrimidine tract binding protein associated
  • PTB-associated splicing factor
  • protein phosphatase 1, regulatory subunit 140
  • hPOMp100
  • PTB-associated-splicing factor
  • Polypyrimidine tract-binding protein-associated-splicing factor
  • polypyrimidine tract-binding protein-associated splicing factor
  • splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
  • splicing factor proline/glutamine-rich
  • DNA-binding p52/p100 complex, 100 kDa subunit
  • PSF
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Language Label Description Also known as
English
splicing factor proline and glutamine rich
mammalian protein found in Homo sapiens
  • 100 kDa DNA-pairing protein
  • splicing factor, proline- and glutamine-rich
  • epididymis secretory sperm binding protein
  • SFPQ
  • polypyrimidine tract binding protein associated
  • PTB-associated splicing factor
  • protein phosphatase 1, regulatory subunit 140
  • hPOMp100
  • PTB-associated-splicing factor
  • Polypyrimidine tract-binding protein-associated-splicing factor
  • polypyrimidine tract-binding protein-associated splicing factor
  • splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
  • splicing factor proline/glutamine-rich
  • DNA-binding p52/p100 complex, 100 kDa subunit
  • PSF

Statements

molecular function
protein binding
determination method
IPI
15 references
retrieved
8 April 2019
stated in
The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation
GOA
curator
UniProt
UniProt protein ID
P23246
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis
GOA
curator
UniProt
UniProt protein ID
P23246
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
Transcription of the human microsomal epoxide hydrolase gene (EPHX1) is regulated by an HNF-4α/CAR/RXR/PSF complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
retrieved
8 April 2019
stated in
hnRNP M interacts with PSF and p54(nrb) and co-localizes within defined nuclear structures
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23246
determination method
IPI
cell component
biological process

Identifiers

MeSH descriptor ID
D000072670
subject named as
PTB-Associated Splicing Factor
0 references
 
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