methyl-CpG binding protein 2 (Q21113404)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P51608

methyl-CpG binding protein MeCP2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P51608

Methyl-CpG DNA binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

double-stranded methylated DNA binding

3 references

17 October 2017

Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

transcription corepressor activity

1 reference

8 April 2019

Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

protein domain specific binding

TAS

1 reference

8 April 2019

The Ski protein family is required for MeCP2-mediated transcriptional repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

protein N-terminus binding

IPI

1 reference

8 April 2019

The Ski protein family is required for MeCP2-mediated transcriptional repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

DNA-binding transcription factor activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

transcription factor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

4 references

8 April 2019

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

4 references

17 October 2017

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

1 reference

17 October 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

5 references

8 April 2019

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

double-stranded methylated DNA binding

HDA

4 references

8 April 2019

Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 references

17 October 2017

Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

The Ski protein family is required for MeCP2-mediated transcriptional repression

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

Mutations in ANKRD11 cause KBG syndrome, characterized by intellectual disability, skeletal malformations, and macrodontia

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

1 reference

17 October 2017

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization

gamma-tubulin complex

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

1 reference

8 April 2019

Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

The Ski protein family is required for MeCP2-mediated transcriptional repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

9 references

8 April 2019

Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

The Ski protein family is required for MeCP2-mediated transcriptional repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

Mutations in ANKRD11 cause KBG syndrome, characterized by intellectual disability, skeletal malformations, and macrodontia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

negative regulation of neuron apoptotic process

TAS

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

multicellular organismal response to stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

inositol metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

mitochondrial electron transport, ubiquinol to cytochrome c

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

post-embryonic development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

neuron projection development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

regulation of gene expression by genetic imprinting

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

neuromuscular process controlling posture

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

adult locomotory behavior

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

transcription, DNA-templated

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

ventricular system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

glutamine metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

neuromuscular process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

excitatory postsynaptic potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

nervous system process involved in regulation of systemic arterial blood pressure

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

chemical synaptic transmission

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

negative regulation of histone methylation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

glucocorticoid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

behavioral fear response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

respiratory gaseous exchange by respiratory system

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

cerebellum development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

regulation of synaptic plasticity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

cardiolipin metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

neuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

sensory perception of pain

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

phosphatidylcholine metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

regulation of gene expression, epigenetic

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

cellular biogenic amine metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

regulation of respiratory gaseous exchange by nervous system process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

negative regulation of histone acetylation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

catecholamine secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

long-term potentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

positive regulation of synapse assembly

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

negative regulation of smooth muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

positive regulation of histone H3-K9 trimethylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

mitotic spindle organization

1 reference

8 April 2019

Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51608&geneProductId=UniProtKB:P51608

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IBA

response to radiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

positive regulation of G2/M transition of mitotic cell cycle

IBA

1 reference

8 April 2019

Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

positive regulation of microtubule nucleation

IMP

1 reference

8 April 2019

Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

negative regulation of transcription by RNA polymerase II

IMP

3 references

8 April 2019

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

transcription initiation from RNA polymerase II promoter

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

negative regulation of gene expression

TAS

1 reference

8 April 2019

MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

negative regulation of angiogenesis

1 reference

8 April 2019

MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

negative regulation of blood vessel endothelial cell migration

IMP

1 reference

8 April 2019

MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

positive regulation of DNA methylation

1 reference

8 April 2019

MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51608

has part(s)

Methyl-CpG DNA binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P51608

Identifiers

MeSH descriptor ID

C497392

subject named as

MECP2 protein, human

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata