Eukaryotic translation elongation factor 1 alpha 1 (Q21109284)

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mammalian protein found in Homo sapiens
  • cervical cancer suppressor 3
  • translation elongation factor 1 alpha 1-like 14
  • epididymis secretory sperm binding protein
  • CTCL tumor antigen
  • leukocyte receptor cluster member 7
  • EF-1-alpha-1
  • elongation factor Tu
  • leukocyte receptor cluster (LRC) member 7
  • EEF1A1
  • eukaryotic elongation factor 1 A-1
  • prostate tumor-inducing protein 1
  • eukaryotic translation elongation factor 1 alpha 1-like 14
  • eEF1A-1
  • elongation factor 1 alpha subunit
  • EF-Tu
  • elongation factor 1-alpha 1
  • EF1a-like protein
  • glucocorticoid receptor AF-1 specific elongation factor
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Language Label Description Also known as
English
Eukaryotic translation elongation factor 1 alpha 1
mammalian protein found in Homo sapiens
  • cervical cancer suppressor 3
  • translation elongation factor 1 alpha 1-like 14
  • epididymis secretory sperm binding protein
  • CTCL tumor antigen
  • leukocyte receptor cluster member 7
  • EF-1-alpha-1
  • elongation factor Tu
  • leukocyte receptor cluster (LRC) member 7
  • EEF1A1
  • eukaryotic elongation factor 1 A-1
  • prostate tumor-inducing protein 1
  • eukaryotic translation elongation factor 1 alpha 1-like 14
  • eEF1A-1
  • elongation factor 1 alpha subunit
  • EF-Tu
  • elongation factor 1-alpha 1
  • EF1a-like protein
  • glucocorticoid receptor AF-1 specific elongation factor

Statements

molecular function
protein binding
determination method
IPI
15 references
retrieved
8 April 2019
stated in
The possible interaction of CDA14 and protein elongation factor 1alpha
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
eEF1A mediates the nuclear export of SNAG-containing proteins via the Exportin5-aminoacyl-tRNA complex
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
Elongation factor-1A1 is a novel substrate of the protein phosphatase 1-TIMAP complex
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
The SAM domain of the RhoGAP DLC1 binds EF1A1 to regulate cell migration
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
Evidence for distinct functions for human DNA repair factors hHR23A and hHR23B
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
A novel cervical cancer suppressor 3 (CCS-3) interacts with the BTB domain of PLZF and inhibits the cell growth by inducing apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
Novel interaction partners of Bardet-Biedl syndrome proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
HDM2-binding partners: interaction with translation elongation factor EF1alpha
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
Guanine nucleotides regulate sphingosine kinase 1 activation by eukaryotic elongation factor 1A and provide a mechanism for eEF1A-associated oncogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
retrieved
8 April 2019
stated in
Novel interaction partners of Bardet-Biedl syndrome proteins
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IPI
cell component
cytoplasm
determination method
IDA
ISS
TAS
IEA
9 references
retrieved
8 April 2019
stated in
The primary structure of the alpha subunit of human elongation factor 1. Structural aspects of guanine-nucleotide-binding sites
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IEA
retrieved
8 April 2019
stated in
Immunofluorescence studies of human fibroblasts demonstrate the presence of the complex of elongation factor-1 beta gamma delta in the endoplasmic reticulum
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
8 April 2019
stated in
The possible interaction of CDA14 and protein elongation factor 1alpha
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
8 April 2019
stated in
eEF1A mediates the nuclear export of SNAG-containing proteins via the Exportin5-aminoacyl-tRNA complex
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
8 April 2019
stated in
Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
8 April 2019
stated in
Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IDA
extracellular exosome
determination method
IDA
5 references
retrieved
26 September 2017
stated in
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
26 September 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
26 September 2017
stated in
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
26 September 2017
stated in
Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
26 September 2017
stated in
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
nucleus
determination method
IDA
IEA
6 references
retrieved
26 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IEA
retrieved
26 September 2017
stated in
Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
26 September 2017
stated in
Immunofluorescence studies of human fibroblasts demonstrate the presence of the complex of elongation factor-1 beta gamma delta in the endoplasmic reticulum
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
26 September 2017
stated in
Proteomic characterization of the human sperm nucleus
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
26 September 2017
stated in
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
26 September 2017
stated in
Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68104&geneProductId=UniProtKB:P68104
determination method
IDA
nucleus
determination method
HDA
IDA
IEA
5 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IEA
retrieved
8 April 2019
stated in
Immunofluorescence studies of human fibroblasts demonstrate the presence of the complex of elongation factor-1 beta gamma delta in the endoplasmic reticulum
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
8 April 2019
stated in
Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
8 April 2019
stated in
Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
IDA
retrieved
8 April 2019
stated in
Proteomic characterization of the human sperm nucleus
GOA
curator
UniProt
UniProt protein ID
P68104
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68104
determination method
HDA
biological process

Identifiers

 
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