Leukotriene A4 hydrolase (Q21104634)

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mammalian protein found in Homo sapiens
  • leukotriene A-4 hydrolase
  • LTA-4 hydrolase
  • testicular secretory protein Li 27
  • LTA4H
  • Leukotriene A(4) hydrolase
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Language Label Description Also known as
English
Leukotriene A4 hydrolase
mammalian protein found in Homo sapiens
  • leukotriene A-4 hydrolase
  • LTA-4 hydrolase
  • testicular secretory protein Li 27
  • LTA4H
  • Leukotriene A(4) hydrolase

Statements

molecular function
leukotriene-A4 hydrolase activity
determination method
IDA
IEA
TAS
6 references
retrieved
26 September 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
TAS
retrieved
26 September 2017
stated in
Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
TAS
retrieved
26 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
IEA
retrieved
26 September 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
IEA
retrieved
26 September 2017
stated in
Molecular cloning and functional expression of a Caenorhabditis elegans aminopeptidase structurally related to mammalian leukotriene A4 hydrolases
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
IDA
retrieved
26 September 2017
stated in
Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
IDA
zinc ion binding
determination method
IDA
IEA
IMP
TAS
5 references
retrieved
8 April 2019
stated in
Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
TAS
retrieved
8 April 2019
stated in
Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
IEA
retrieved
8 April 2019
stated in
Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
IDA
retrieved
8 April 2019
stated in
Structure-based dissection of the active site chemistry of leukotriene A4 hydrolase: implications for M1 aminopeptidases and inhibitor design
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
IDA
cell component
biological process
leukotriene biosynthetic process
determination method
IDA
IEA
IMP
TAS
5 references
retrieved
26 September 2017
stated in
Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
TAS
retrieved
26 September 2017
stated in
Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
IMP
retrieved
26 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
IEA
retrieved
26 September 2017
stated in
Molecular cloning and functional expression of a Caenorhabditis elegans aminopeptidase structurally related to mammalian leukotriene A4 hydrolases
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
IDA
retrieved
26 September 2017
stated in
Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P09960&geneProductId=UniProtKB:P09960
determination method
IDA
leukotriene biosynthetic process
determination method
IBA
IDA
IEA
IMP
TAS
6 references
retrieved
8 April 2019
stated in
Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
TAS
retrieved
8 April 2019
stated in
Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
IEA
retrieved
8 April 2019
stated in
Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
IDA
retrieved
8 April 2019
stated in
Molecular cloning and functional expression of a Caenorhabditis elegans aminopeptidase structurally related to mammalian leukotriene A4 hydrolases
GOA
curator
UniProt
UniProt protein ID
P09960
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09960
determination method
IBA

Identifiers

PDB structure ID
 
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