RAD21 cohesin complex component (Q21103064)

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mammalian protein found in Homo sapiens
  • double-strand-break repair protein rad21 homolog
  • kleisin
  • sister chromatid cohesion 1
  • SCC1 homolog
  • protein involved in DNA double-strand break repair
  • RAD21
  • nuclear matrix protein 1
  • NXP-1
  • RAD21 homolog
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Language Label Description Also known as
English
RAD21 cohesin complex component
mammalian protein found in Homo sapiens
  • double-strand-break repair protein rad21 homolog
  • kleisin
  • sister chromatid cohesion 1
  • SCC1 homolog
  • protein involved in DNA double-strand break repair
  • RAD21
  • nuclear matrix protein 1
  • NXP-1
  • RAD21 homolog

Statements

molecular function
protein binding
determination method
IPI
21 references
retrieved
8 April 2019
stated in
Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates
GOA
curator
UniProt
UniProt protein ID
O60216
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA
GOA
curator
UniProt
UniProt protein ID
O60216
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Releasing cohesin from chromosome arms in early mitosis: opposing actions of Wapl-Pds5 and Sgo1
GOA
curator
UniProt
UniProt protein ID
O60216
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells
GOA
curator
UniProt
UniProt protein ID
O60216
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Processing, localization, and requirement of human separase for normal anaphase progression
GOA
curator
UniProt
UniProt protein ID
O60216
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Cohesin mediates transcriptional insulation by CCCTC-binding factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Systematic analysis of human protein complexes identifies chromosome segregation proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Wapl controls the dynamic association of cohesin with chromatin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
The hsSsu72 phosphatase is a cohesin-binding protein that regulates the resolution of sister chromatid arm cohesion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Protein requirements for sister telomere association in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
retrieved
8 April 2019
stated in
Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60216
determination method
IPI
cell component
biological process

Identifiers

 
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