Embryonic ectoderm development (Q21097479)

WD40-repeat-containing domain superfamily

1 reference

stated in

WD40/YVTN repeat-like-containing domain superfamily

1 reference

stated in

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

16 references

8 April 2019

Mutations in genes encoding polycomb repressive complex 2 subunits cause Weaver syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Corepressor protein CDYL functions as a molecular bridge between polycomb repressor complex 2 and repressive chromatin mark trimethylated histone lysine 27

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Role of the polycomb repressive complex 2 in acute promyelocytic leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

The Polycomb group protein EZH2 directly controls DNA methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

A High-Density Map for Navigating the Human Polycomb Complexome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

identical protein binding

IPI

1 reference

8 April 2019

The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

histone methyltransferase activity

histone methyltransferase activity (H3-K27 specific)

IDA

IMP

1 reference

27 February 2018

Mutations in genes encoding polycomb repressive complex 2 subunits cause Weaver syndrome

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

histone methyltransferase activity

IBA

3 references

8 April 2019

Mutations in genes encoding polycomb repressive complex 2 subunits cause Weaver syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

6 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

27 February 2018

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

27 February 2018

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

27 February 2018

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

27 February 2018

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

3 references

8 April 2019

Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

regulation of gene expression by genetic imprinting

IBA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

regulation of transcription, DNA-templated

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

negative regulation of transcription by RNA polymerase II

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

transcription, DNA-templated

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530

negative regulation of gene expression, epigenetic

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

TAS

spinal cord development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

positive regulation of histone H3-K27 methylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

regulation of adaxial/abaxial pattern formation

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

histone H3-K27 methylation

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

cellular response to leukemia inhibitory factor

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

negative regulation of G0 to G1 transition

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530

TAS

chromatin organization

1 reference

8 April 2019

1 reference

WD40 repeat, conserved site

1 reference

stated in

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016