Identification of novel functional inhibitors of acid sphingomyelinase (Q21003953)

8 July 2022

9

Teja W Groemer

Teja W

Groemer

1 reference

8 July 2022

11

Klaus R Liedl

Klaus R

Liedl

1 reference

8 July 2022

3

Stefan Trapp

Stefan

Trapp

1 reference

8 July 2022

12

Erich Gulbins

Erich

Gulbins

1 reference

8 July 2022

Christiane Mühle

7

Christiane

Mühle

1 reference

8 July 2022

Markus Muehlbacher

2

Markus

Muehlbacher

1 reference

8 July 2022

Stefanie Pechmann

4

Stefanie

Pechmann

1 reference

8 July 2022

Astrid Friedl

5

Astrid

Friedl

1 reference

8 July 2022

Martin Reichel

6

Martin

Reichel

1 reference

8 July 2022

Lothar Terfloth

8

Lothar

Terfloth

1 reference

8 July 2022

Gudrun M Spitzer

10

Gudrun M

Spitzer

1 reference

8 July 2022

Philipp Tripal

13

Philipp

Tripal

1 reference

Creative Commons Attribution 4.0 International

8 July 2022

language of work or name

English

0 references

publication date

2011

0 references

published in

PLOS One

0 references

volume

6

0 references

issue

8

0 references

page(s)

e23852

0 references

copyright license

start time

31 August 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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12 September 2017

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12 September 2017

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Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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27 September 2017

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Reactive nitrogen and oxygen species activate different sphingomyelinases to induce apoptosis in airway epithelial cells

27 September 2017

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New insights on the use of desipramine as an inhibitor for acid ceramidase

27 September 2017

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27 September 2017

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27 September 2017

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30 May 2018

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30 May 2018

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Sphingosine-1-phosphate in cell growth and cell death

30 May 2018

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30 May 2018

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Changes in bioactive lipids, alkylacylglycerol and ceramide, occur in HIV-infected cells

30 May 2018

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30 May 2018

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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21 January 2018

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Ceramide pathways modulate ethanol-induced cell death in astrocytes

21 January 2018

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21 January 2018

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Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice.

29 November 2018

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Therapeutic efficacy and safety of amitriptyline in patients with cystic fibrosis.

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Benchmarking and validating algorithms that estimate pK(a) values of drugs based on their molecular structures.

21 January 2018

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Wrappers for feature subset selection

21 January 2018

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Estimation of the Youden Index and its associated cutoff point

21 January 2018

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Random forest: a classification and regression tool for compound classification and QSAR modeling

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Novel 2D fingerprints for ligand-based virtual screening

21 January 2018

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In silico ADME modelling: prediction models for blood-brain barrier permeation using a systematic variable selection method

21 January 2018

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In silico prediction of blood brain barrier permeability: an Artificial Neural Network model.

21 January 2018

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Modeling blood-brain barrier partitioning using the electrotopological state

21 January 2018

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Parameterization of an empirical model for the prediction of n-octanol, alkane and cyclohexane/water as well as brain/blood partition coefficients

21 January 2018

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SuperDrug: a conformational drug database

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Predicting blood-brain barrier penetration from molecular weight and number of polar atoms

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Development of quantitative structure-property relationship models for early ADME evaluation in drug discovery. 2. Blood-brain barrier penetration.

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CD95-mediated apoptosis in vivo involves acid sphingomyelinase.

21 January 2018

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Tricyclic antidepressants induce sphingomyelinase deficiency in fibroblast and neuroblastoma cell cultures

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The new classification of drugs: the ATC-code now introduced

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Measurement of sphingomyelinase activity

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Identifiers

DOI

10.1371/JOURNAL.PONE.0023852

0 references

ADS bibcode

2011PLoSO...623852K

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Fatcat ID

release_huuphtzqtvbo5d2fquff2xga3u

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PMC publication ID

3166082

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