eigengene (Q113330977)

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one of a set of right singular vectors of a genes x samples matrix that tabulates, e.g., the mRNA or gene expression of the genes across the samples
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    English
    eigengene
    one of a set of right singular vectors of a genes x samples matrix that tabulates, e.g., the mRNA or gene expression of the genes across the samples

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      2 references
      September 2015
      Dr. Orly Alter
      Dr. Orly Alter is a USTAR associate professor of bioengineering and human genetics at the Scientific Computing and Imaging Institute and the Huntsman Cancer Institute at the University of Utah. Inventor of the "eigengene," she pioneered the matrix and tensor modeling of large-scale molecular biological data, which, as she demonstrated, can be used to correctly predict previously unknown cellular mechanisms. (English)
      1990s
      2 references
      1999, Orly Alter et al., ‘‘Singular Value Decomposition for Gene Expression Data Processing and Modeling.’’ In: After the Genome V (December 6–10, 1999, Jackson Hole, WY) (English)
      We describe the use of singular value decomposition in transforming gene expression data from genes/arrays space to ‘‘eigengenes’’/‘‘eigenarrays’’ space, where the eigengenes and eigenarrays are unique orthonormal superpositions of the genes and arrays, respectively. (English)
      Alter Lab (English)
      We describe the use of singular value decomposition in transforming gene expression data from genes/arrays space to ‘‘eigengenes’’/‘‘eigenarrays’’ space, where the eigengenes and eigenarrays are unique orthonormal superpositions of the genes and arrays, respectively. (English)
       
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