Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma (Q102075251)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

title

Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Maria Valieva

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Salaheddine Ali

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Rocio Chamorro González

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Yi Bei

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Heathcliff Dorado García

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Elias Rodriguez-Fos

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Montserrat Puiggròs

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Kerstin Haase

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Celine Y Chen

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Luis P Kuschel

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Philipp Euskirchen

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Michael I Robson

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Joern Toedling

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Annabell Szymansky

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Matthias Fischer

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Johannes H Schulte

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Anton Henssen

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Richard Koche

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

27

Stefan Mundlos

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

author name string

Robert Schöpflin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Claudia Röefzaad

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Katharina Kasack

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Csilla Keskeny

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Verena Heinrich

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Carolina Rosswog

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Falk Hertwig

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

David Torrents

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Angelika Eggert

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

publication date

16 November 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

page(s)

5823

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

18 November 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Chromothripsis from DNA damage in micronuclei.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Exploring the landscape of focal amplifications in cancer using AmpliconArchitect

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Structure and evolution of double minutes in diagnosis and relapse brain tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

The landscape of genomic alterations across childhood cancers.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Functional Enhancers Shape Extrachromosomal Oncogene Amplifications

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Telomerase activation by genomic rearrangements in high-risk neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Activation of proto-oncogenes by disruption of chromosome neighborhoods.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Histone H3K27ac separates active from poised enhancers and predicts developmental state

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Meta-mining of copy number profiles of high-risk neuroblastoma tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Regulatory Landscaping: How Enhancer-Promoter Communication Is Sculpted in 3D

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Detecting DNA cytosine methylation using nanopore sequencing.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Circular ecDNA promotes accessible chromatin and high oncogene expression

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Topology of double minutes (dmins) and homogeneously staining regions (HSRs) in nuclei of human neuroblastoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Formation of new chromatin domains determines pathogenicity of genomic duplications

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

STAR: ultrafast universal RNA-seq aligner

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Chromatin immunoprecipitation and microarray-based analysis of protein location

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Fast and accurate long-read alignment with Burrows-Wheeler transform

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

deepTools2: a next generation web server for deep-sequencing data analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Identifying ChIP-seq enrichment using MACS.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

TFBSTools: an R/bioconductor package for transcription factor binding site analysis.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assembly

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

A fast algorithm for matrix balancing

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Effective normalization for copy number variation in Hi-C data

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

SvABA: genome-wide detection of structural variants and indels by local assembly.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

NanoPack: visualizing and processing long-read sequencing data

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Assembly of long, error-prone reads using repeat graphs

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Minimap2: pairwise alignment for nucleotide sequences

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Bandage: interactive visualization of de novo genome assemblies

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Ribbon: Intuitive visualization for complex genomic variation

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

A sensitive assay for dNTPs based on long synthetic oligonucleotides, EvaGreen dye and inhibitor-resistant high-fidelity DNA polymerase

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Rawcopy: Improved copy number analysis with Affymetrix arrays

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

The ENCODE Blacklist: Identification of Problematic Regions of the Genome

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-19452-Y

7 January 2021

10.1038/S41467-020-19452-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199677%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

0 references

0 references

1 reference