lopinafir (Q422585)

Dynodwr Drugbank (Alberta)

dyddiad cyhoeddi

17 Tachwedd 2015

01601

adeiledd gemegol

Lopinavir.svg
1,800 × 1,900; 27 KB

1 ffynhonnell

mewnforiwyd o

Wicipedia Almaeneg

màs

628.362 uned Dalton

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

Lopinavir (Saesneg)

19 Hydref 2016

stereoisomer of ^Saesneg

(2R) epimer-lopinavir ^Saesneg

2 ffynonellau

inferred from InChIKey ^Saesneg

inferred from InChI ^Saesneg

(4R) epimer-lopinavir ^Saesneg

2 ffynonellau

inferred from InChIKey ^Saesneg

inferred from InChI ^Saesneg

D-valine diastereomer-lopinavir ^Saesneg

2 ffynonellau

inferred from InChIKey ^Saesneg

inferred from InChI ^Saesneg

(2R,4R) diastereomer-lopinavir ^Saesneg

1 ffynhonnell

inferred from InChI ^Saesneg

fformwla gemegol

C₃₇H₄₈N₄O₅

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

Lopinavir (Saesneg)

19 Tachwedd 2016

CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)NC(=O)C(C(C)C)N4CCCNC4=O)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

Lopinavir (Saesneg)

19 Tachwedd 2016

isomeric SMILES ^Saesneg

CC1=C(C(=CC=C1)C)OCC(=O)N[C@@H](CC2=CC=CC=C2)[C@H](C[C@H](CC3=CC=CC=C3)NC(=O)[C@H](C(C)C)N4CCCNC4=O)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

Lopinavir (Saesneg)

19 Tachwedd 2016

inhibitor of ^Saesneg

Plasmodium falciparum hexose transporter ^Saesneg

1 ffynhonnell

The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir. ^Saesneg

World Health Organisation international non-proprietary name ^Saesneg

Lopinavir (Saesneg)

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

syndrom diffyg imiwnolegol caffaeledig

Lopinavir (Saesneg)

19 Ionawr 2016

1 ffynhonnell

NDF-RT ^Saesneg

NDF-RT

N0000148672

feirws imiwnoddiffygiant dynol

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

NDF-RT

N0000148672

Lopinavir-ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

significant drug interaction ^Saesneg

bosentan

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

carbamasepin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

riffabwtin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

riffampisin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

riffapentin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

erythromycin

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

methadon

side effect ^Saesneg

withdrawal symptom ^Saesneg

1 ffynhonnell

yn ôl pob tebyg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

bwprenorffin

side effect ^Saesneg

central respiratory depression ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

clarithromycin

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

posaconazole ^Saesneg

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

rosuvastatin ^Saesneg

side effect ^Saesneg

rhabdomyolysis ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

rosuvastatin ^Saesneg

side effect ^Saesneg

muscular disease ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

atorfastatin

side effect ^Saesneg

rhabdomyolysis ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

atorfastatin

side effect ^Saesneg

muscular disease ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

cetoconasol

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

established ^Saesneg

categori beichiogrwydd Unol Daleithiau America C

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

categori beichiogrwydd

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

LiverTox likelihood score ^Saesneg

LiverTox toxicity likelihood category D ^Saesneg

1 ffynhonnell

LiverTox ^Saesneg

https://www.ncbi.nlm.nih.gov/books/n/livertox/Lopinavir

8 Ebrill 2021

cyfeirnod URL

last update ^Saesneg

1 Medi 2017

rôl y pwnc

xenobiotic-transporting ATPase inhibitor ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

5 Mawrth 2018

HIV protease inhibitors ^Saesneg

2 ffynonellau

NDF-RT ^Saesneg

5 Mawrth 2018

15 Mawrth 2018

cytochrome P-450 CYP3A inhibitors ^Saesneg

1 ffynhonnell

15 Mawrth 2018

0 ffynonellau

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

1 ffynhonnell

ChEBI ^Saesneg

Lopinavir

0 ffynonellau

catalog

CAS COVID-19 Anti-Viral Candidate Compounds ^Saesneg

0 ffynonellau

Identifiers

InChI

InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

Lopinavir (Saesneg)

KJHKTHWMRKYKJE-SUGCFTRWSA-N

19 Tachwedd 2016

InChIKey ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

Lopinavir (Saesneg)

19 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

192725-17-0

2 ffynonellau

UNII ^Saesneg

lopinavir (Saesneg)

KJHKTHWMRKYKJE-SUGCFTRWSA-N

19 Tachwedd 2016

InChIKey ^Saesneg

CAS Common Chemistry ^Saesneg

https://commonchemistry.cas.org/detail?cas_rn=192725-17-0

9 Ebrill 2021

cyfeirnod URL

ChemSpider ID ^Saesneg

83706

1 ffynhonnell

ChemSpider ^Saesneg

ChemSpider ID ^Saesneg

83706

Lopinavir (Saesneg)

19 Tachwedd 2016

PubChem CID ^Saesneg

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

Lopinavir (Saesneg)

19 Tachwedd 2016

Reaxys registry number ^Saesneg

9309881

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

lopinavir (Saesneg)

19 Hydref 2016

ChEBI ID ^Saesneg

mapping relation type ^Saesneg

exact match ^Saesneg

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

LOPINAVIR (Saesneg)

19 Tachwedd 2016

ChEMBL ID ^Saesneg

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

LOPINAVIR (Saesneg)

19 Tachwedd 2016

UniChem compound ID ^Saesneg

200615

1 ffynhonnell

MSBNK-Athens_Univ-AU228801

UniChem ^Saesneg

MassBank accession ID ^Saesneg

0 ffynonellau

MSBNK-Athens_Univ-AU228802

0 ffynonellau

MSBNK-Athens_Univ-AU228803

0 ffynonellau

MSBNK-Athens_Univ-AU228804

0 ffynonellau

MSBNK-Athens_Univ-AU228805

0 ffynonellau

MSBNK-Athens_Univ-AU228806

0 ffynonellau

SPLASH ^Saesneg

splash10-0532-1900601000-f85a252f1640f27563a8

0 ffynonellau

dynodwr HSDB

8138

1 ffynhonnell

Hazardous Substances Data Bank ^Saesneg

28 Hydref 2019

Lopinavir (Saesneg)

10 Mai 2021

DSSTox substance ID ^Saesneg

DTXSID8046456

1 ffynhonnell

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Saesneg

DSSTOX compound identifier ^Saesneg

DTXCID6026456

0 ffynonellau

LiverTox ID ^Saesneg

Lopinavir

0 ffynonellau

ECHA Substance Infocard ID ^Saesneg

0 ffynonellau

Lopinavir

0 ffynonellau

MeSH concept ID ^Saesneg

M0558541

0 ffynonellau

Cod MeSH

D03.383.742.698.553

0 ffynonellau

RxNorm ID ^Saesneg

195088

1 ffynhonnell

UNII ^Saesneg

lopinavir (Saesneg)

Dynodwr Drugbank (Alberta)

19 Tachwedd 2016

01601

1 ffynhonnell

Dynodwr Drugbank (Alberta)

DrugBank ^Saesneg

01601

Lopinavir (Saesneg)

19 Tachwedd 2016

1 ffynhonnell

inferred from InChIKey ^Saesneg

UNII ^Saesneg

1 ffynhonnell

UNII ^Saesneg

lopinavir (Saesneg)

19 Tachwedd 2016

1 ffynhonnell

UNII ^Saesneg

lopinavir (Saesneg)

19 Tachwedd 2016

Probes And Drugs ID ^Saesneg

PD009457

0 ffynonellau

DrugCentral ID ^Saesneg

1 ffynhonnell

UniChem ^Saesneg

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

lopinavir (Saesneg)

19 Hydref 2016

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

lopinavir (Saesneg)

19 Hydref 2016

IEDB Epitope ID ^Saesneg

231715

1 ffynhonnell

dynodwr Microsoft Academic

Immune Epitope Database and Analysis Resource ^Saesneg

IEDB Epitope ID ^Saesneg

1 Mawrth 2022

0 ffynonellau

DeCS ID ^Saesneg

0 ffynonellau

1 ffynhonnell

Freebase Data Dumps ^Saesneg

28 Hydref 2013

1 ffynhonnell

KBpedia ^Saesneg

9 Gorffennaf 2020

2777182164

0 ffynonellau

OpenAlex ID ^Saesneg

1 ffynhonnell

OpenAlex ^Saesneg

26 Ionawr 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID ^Saesneg

1MUI

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1MUI

1MUI (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2RKG

2RKG (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2RKF

2RKF (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1RV7

1RV7 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2Q5K

2Q5K (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2O4S

2O4S (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3OGQ

3OGQ (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2QHC

2QHC (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4L1A

4L1A (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2Z54

2Z54 (Saesneg)

19 Hydref 2016

UMLS CUI ^Saesneg

C0674432

1 ffynhonnell

UNII ^Saesneg

lopinavir (Saesneg)