riffabwtin (Q1135705)

Dynodwr Drugbank (Alberta)

dyddiad cyhoeddi

17 Tachwedd 2015

00615

adeiledd gemegol

Rifabutin structure.svg
512 × 460; 13 KB

0 ffynonellau

màs

846.442 uned Dalton

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

RIFABUTIN (Saesneg)

17 Tachwedd 2016

C₄₆H₆₂N₄O₁₁

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

RIFABUTIN (Saesneg)

17 Tachwedd 2016

CC1C=CC=C(C(=O)NC2=C3C(=NC4(N3)CCN(CC4)CC(C)C)C5=C6C(=C(C(=C5C2=O)O)C)OC(C6=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

RIFABUTIN (Saesneg)

17 Tachwedd 2016

isomeric SMILES ^Saesneg

C[C@H]1/C=C/C=C(\C(=O)NC2=C3C(=NC4(N3)CCN(CC4)CC(C)C)C5=C6C(=C(C(=C5C2=O)O)C)O[C@@](C6=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)/C

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

RIFABUTIN (Saesneg)

https://www.whocc.no/atc_ddd_index/?code=J04AB04

17 Tachwedd 2016

defined daily dose ^Saesneg

0.15 gram

dull gweini

gweini genau

1 ffynhonnell

cyfeirnod URL

cynhwysyn actif yn

Mycobutin ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

227450

14 Chwefror 2018

World Health Organisation international non-proprietary name ^Saesneg

rifabutin (Saesneg)

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

Rifabutin (Saesneg)

19 Ionawr 2016

found in taxon ^Saesneg

Streptomyces ^Saesneg

1 ffynhonnell

Ansamycin antibiotics as free radical scavengers isolated from Streptomyces by using the bactericidal action of the hydroxyl radical ^Saesneg

clefyd a drinir

y darfodedigaeth ysgyfeiniol

1 ffynhonnell

NDF-RT ^Saesneg

NDF-RT

N0000148321

clefyd gwyllt mycobacteriwm

13 Rhagfyr 2016

2 ffynonellau

NDF-RT ^Saesneg

NDF-RT

N0000148321

13 Rhagfyr 2016

Drug Indications Extracted from FAERS ^Saesneg

2 Hydref 2018

significant drug interaction ^Saesneg

clarithromycin

side effect ^Saesneg

uveitis ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

side effect ^Saesneg

uveitis ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

side effect ^Saesneg

nam ar y golwg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

side effect ^Saesneg

dallineb

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

side effect ^Saesneg

photophobia ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

side effect ^Saesneg

eye pain ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

cobicistat ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

categori beichiogrwydd Awstralia C

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

categori beichiogrwydd

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

categori beichiogrwydd Unol Daleithiau America B

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

LiverTox likelihood score ^Saesneg

LiverTox toxicity likelihood category D ^Saesneg

1 ffynhonnell

LiverTox ^Saesneg

https://www.ncbi.nlm.nih.gov/books/n/livertox/Rifabutin

8 Ebrill 2021

cyfeirnod URL

last update ^Saesneg

10 Mehefin 2018

gwneuthurwr

Pfizer ^Saesneg

1 ffynhonnell

cyfeirnod URL

https://www.pfizer.com/products/product-list

rôl y pwnc

DNA polymerase inhibitors ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

5 Mawrth 2018

1 ffynhonnell

15 Mawrth 2018

antitubercular antibiotics ^Saesneg

1 ffynhonnell

15 Mawrth 2018

0 ffynonellau

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

45367

‎WHO Aware Classification ^Saesneg

watch ^Saesneg

1 ffynhonnell

InChI=1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14-/t23-,25+,26+,27+,30-,37-,38+,41+,45-/m0/s1

2023 ‎AWaRe classification‎ ^Saesneg

categori Comin

Rifabutin

0 ffynonellau

Identifiers

InChI

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

RIFABUTIN (Saesneg)

ATEBXHFBFRCZMA-VXTBVIBXSA-N

17 Tachwedd 2016

InChIKey ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

RIFABUTIN (Saesneg)

17 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

72559-06-9

1 ffynhonnell

Global Substance Registration System ^Saesneg

UNII ^Saesneg

1W306TDA6S

rifabutin (Saesneg)

17 Tachwedd 2016

ChemSpider ID ^Saesneg

10482168

1 ffynhonnell

ChemSpider ^Saesneg

ChemSpider ID ^Saesneg

10482168

RIFABUTIN (Saesneg)

19 Hydref 2016

PubChem CID ^Saesneg

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

RIFABUTIN (Saesneg)

17 Tachwedd 2016

ChEBI ID ^Saesneg

45367

mapping relation type ^Saesneg

exact match ^Saesneg

2 ffynonellau

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

RIFABUTIN (Saesneg)

17 Tachwedd 2016

ChEBI release 2019-10-02 ^Saesneg

ChEMBL ID ^Saesneg

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

RIFABUTIN (Saesneg)

seiliwyd ar dybiaethau esboniadol

17 Tachwedd 2016

SureChEMBL ID ^Saesneg

SCHEMBL36043

1 ffynhonnell

inferred from InChIKey ^Saesneg

dynodwr HSDB

3577

1 ffynhonnell

Hazardous Substances Data Bank ^Saesneg

28 Hydref 2019

RIFABUTIN (Saesneg)

10 Mai 2021

DSSTox substance ID ^Saesneg

DTXSID0033960

1 ffynhonnell

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Saesneg

DSSTOX compound identifier ^Saesneg

DTXCID5010773

0 ffynonellau

LiverTox ID ^Saesneg

Rifabutin

0 ffynonellau

EC number ^Saesneg

615-780-3

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

100.133.627

27 Rhagfyr 2018

Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione, 16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)- (Saesneg)

dyfyniad

CAS no.: 72559-06-9 (Saesneg)

ECHA Substance Infocard ID ^Saesneg

100.133.627

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

100.133.627

27 Rhagfyr 2018

Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione, 16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)- (Saesneg)

dyfyniad

CAS no.: 72559-06-9 (Saesneg)

Cod yr ATC

J04AB04

1 ffynhonnell

Dynodwr Drugbank (Alberta)

DrugBank ^Saesneg

00615