ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome (Q94947170)

PubMed ID

32414646

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json

20 May 2020

2 references

13 July 2022

22 October 2022

ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome (English)

1 reference

PubMed ID

32414646

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json

20 May 2020

1 reference

1 reference

3

Didier Raoult

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

author name string

Christian A Devaux

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

Jean-Marc Rolain

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

publication date

6 May 2020

1 reference

PubMed ID

32414646

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json

Journal of Microbiology Immunology and Infection

20 May 2020

1 June 2020

2 references

13 July 2022

22 October 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json

Single-cell RNA Expression Profiling of ACE2, The Receptor of SARS-CoV-2

27 May 2020

cites work

1 reference

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Increasing Host Cellular Receptor-Angiotensin-Converting Enzyme 2 (ACE2) Expression by Coronavirus may Facilitate 2019-nCoV (or SARS-CoV-2) Infection

10 February 2021

1 reference

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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

10 February 2021

1 reference

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An emergent clade of SARS-CoV-2 linked to returned travellers from Iran

10 February 2021

1 reference

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Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic

10 February 2021

1 reference

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Coronavirus Disease 2019 (COVID-19) Infection and Renin Angiotensin System Blockers

10 February 2021

1 reference

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Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19

10 February 2021

1 reference

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Antihypertensive drugs and risk of COVID-19? - Authors' reply

10 February 2021

1 reference

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Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

10 February 2021

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COVID-19 and Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers: What Is the Evidence?

10 February 2021

1 reference

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Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection

10 February 2021

1 reference

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Predicting the angiotensin converting enzyme 2 (ACE2) utilizing capability as the receptor of SARS-CoV-2

10 February 2021

1 reference

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New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

10 February 2021

1 reference

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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

10 February 2021

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Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?

10 February 2021

1 reference

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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

10 February 2021

1 reference

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COVID-19 and the cardiovascular system

10 February 2021

1 reference

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Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations

10 February 2021

1 reference

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Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

10 February 2021

1 reference

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Clinical Characteristics of Coronavirus Disease 2019 in China

10 February 2021

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Understanding of COVID-19 based on current evidence

10 February 2021

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High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa

10 February 2021

1 reference

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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

10 February 2021

1 reference

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A pneumonia outbreak associated with a new coronavirus of probable bat origin

10 February 2021

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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

10 February 2021

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A Novel Coronavirus from Patients with Pneumonia in China, 2019

10 February 2021

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Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus

10 February 2021

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The E-Cadherin Cleavage Associated to Pathogenic Bacteria Infections Can Favor Bacterial Invasion and Transmigration, Dysregulation of the Immune Response and Cancer Induction in Humans

10 February 2021

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Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins ()

10 February 2021

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The combination of ACE I/D and ACE2 G8790A polymorphisms revels susceptibility to hypertension: A genetic association study in Brazilian patients

10 February 2021

1 reference

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Sex differences in the metabolic effects of the renin-angiotensin system

10 February 2021

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Association of ACE2 genetic polymorphisms with hypertension-related target organ damages in south Xinjiang

10 February 2021

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Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology

10 February 2021

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Human Coronavirus NL63 Molecular Epidemiology and Evolutionary Patterns in Rural Coastal Kenya.

10 February 2021

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Bats, Coronaviruses, and Deforestation: Toward the Emergence of Novel Infectious Diseases?

10 February 2021

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AMPK Phosphorylation of ACE2 in Endothelium Mitigates Pulmonary Hypertension.

10 February 2021

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Epidemiology characteristics of human coronaviruses in patients with respiratory infection symptoms and phylogenetic analysis of HCoV-OC43 during 2010-2015 in Guangzhou.

10 February 2021

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Epidemiology and clinical characteristics of human coronaviruses OC43, 229E, NL63, and HKU1: a study of hospitalized children with acute respiratory tract infection in Guangzhou, China.

10 February 2021

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KLK5 induces shedding of DPP4 from circulatory Th17 cells in type 2 diabetes

10 February 2021

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Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus

10 February 2021

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10 February 2021

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Exenatide induces an increase in vasodilatory and a decrease in vasoconstrictive mediators.

10 February 2021

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10 February 2021

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A dipeptidyl peptidase-4 inhibitor ameliorates hypertensive cardiac remodeling via angiotensin-II/sodium-proton pump exchanger-1 axis.

10 February 2021

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Angiotensin converting enzyme 2 and diminazene: role in cardiovascular and blood pressure regulation

10 February 2021

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Angiotensin II Stimulation of DPP4 Activity Regulates Megalin in the Proximal Tubules

10 February 2021

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10 February 2021

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10 February 2021

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Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative Stress

10 February 2021

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10 February 2021

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10 February 2021

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Allergic Lung Inflammation Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice.

10 February 2021

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Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection

10 February 2021

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Human monocyte subsets exhibit divergent angiotensin I-converting activity

10 February 2021

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Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors.

10 February 2021

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10 February 2021

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Urinary angiotensin-converting enzyme 2 in hypertensive patients may be increased by olmesartan, an angiotensin II receptor blocker

10 February 2021

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10 February 2021

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10 February 2021

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10 February 2021

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10 February 2021

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The transcription factor HNF1α induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs

10 February 2021

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10 February 2021

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Diminazene aceturate enhances angiotensin-converting enzyme 2 activity and attenuates ischemia-induced cardiac pathophysiology.

10 February 2021

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10 February 2021

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Oral Angiotensin-(1-7) prevented obesity and hepatic inflammation by inhibition of resistin/TLR4/MAPK/NF-κB in rats fed with high-fat diet.

10 February 2021

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10 February 2021

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10 February 2021

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10 February 2021

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10 February 2021

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ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

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10 February 2021

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Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury.

10 February 2021

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10 February 2021

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Correlation of angiotensin-converting enzyme 2 gene polymorphism with antihypertensive effects of benazepril

10 February 2021

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10 February 2021

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10 February 2021

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Polymorphisms of angiotensin-converting enzyme (ACE) and ACE2 are not associated with orthostatic blood pressure dysregulation in hypertensive patients

10 February 2021

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Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia

10 February 2021

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Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease

10 February 2021

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Angiotensin converting enzyme-2 is protective but downregulated in human and experimental lung fibrosis

10 February 2021

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Correlation of angiotensin-converting enzyme 2 gene polymorphisms with stage 2 hypertension in Han Chinese

10 February 2021

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Structure of testis ACE glycosylation mutants and evidence for conserved domain movement

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10 February 2021

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2).

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Amino acids 270 to 510 of the severe acute respiratory syndrome coronavirus spike protein are required for interaction with receptor

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

The renin-angiotensin-aldosterone system and the kidney: effects on kidney disease

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Molecular mechanisms of inhibition of vascular growth by angiotensin-(1-7).

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Exploring the structure and function of zinc metallopeptidases: old enzymes and new discoveries

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Angiotensin II and the fibroproliferative response to acute lung injury.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

The Genome sequence of the SARS-associated coronavirus

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

The role of ACE2 in cardiovascular physiology

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Role of the intracellular domains of CXCR4 in SDF-1-mediated signaling

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Vascular inflammation and the renin-angiotensin system

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Angiotensin-converting enzyme 2 is an essential regulator of heart function

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Aspects of gene polymorphisms in cardiovascular disease: the renin-angiotensin system

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Caspase-dependent apoptosis of cells expressing the chemokine receptor CXCR4 is induced by cell membrane-associated human immunodeficiency virus type 1 envelope glycoprotein (gp120).

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Counterregulatory actions of angiotensin-(1-7).

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: independence from G protein signaling and importance of coreceptor downmodulation.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Binding of HIV-1 virions or gp120-anti-gp120 immune complexes to HIV-1-infected quiescent peripheral blood mononuclear cells reveals latent infection

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

The cytoplasmic domain of CD4 plays a critical role during the early stages of HIV infection in T-cells

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Frequency of a deletion polymorphism in the gene for angiotensin converting enzyme is increased in African-Americans with hypertension

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Differences in the properties and enzymatic specificities of the two active sites of angiotensin I-converting enzyme (kininase II). Studies with bradykinin and other natural peptides

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

The angiotensin I-converting enzyme

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

A unique signature identifies a family of zinc-dependent metallopeptidases.

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene

10 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7201239

10.1016/J.JMII.2020.04.015

10 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

27 May 2020

COVIDWHO ID

covidwho-186735

0 references

1127385722

1 reference

Dimensions COVID-19 publications, datasets and clinical trials

DOI

10.6084/M9.FIGSHARE.11961063

28 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32414646%20AND%20SRC:MED&resulttype=core&format=json