Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily (Q93927471)

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11 May 2020

title

Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily (English)

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11 May 2020

author name string

J C Gorski

1

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11 May 2020

D R Jones

2

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11 May 2020

M A Hamman

3

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11 May 2020

S A Wrighton

4

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11 May 2020

S D Hall

5

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11 May 2020

publication date

1 September 1999

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11 May 2020

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11 May 2020

volume

29

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11 May 2020

issue

9

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11 May 2020

page(s)

931-944

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Interaction of propoxyphene with diazepam, alprazolam and lorazepam

11 May 2020

cites work

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21 January 2018

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Pharmacokinetics and clinical effects of alprazolam following single and multiple oral doses in patients with panic disorder.

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Contribution of human CYP3A subfamily members to the 6-hydroxylation of chlorzoxazone

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Clinical pharmacokinetics of alprazolam. Therapeutic implications

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Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

21 January 2018

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Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin

21 January 2018

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Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes

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Pharmacodynamic evaluation of the benzodiazepine-oral contraceptive interaction.

21 January 2018

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Cyclosporine metabolism in human liver: identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs.

21 January 2018

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Pharmacokinetic pharmacodynamic evaluation of the combined administration of alprazolam and fluoxetine.

21 January 2018

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Characterization of six in vitro reactions mediated by human cytochrome P450: application to the testing of cytochrome P450-directed antibodies

21 January 2018

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Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site.

21 January 2018

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Pharmacokinetics and pharmacodynamics of alprazolam after oral and IV administration

21 January 2018

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Alprazolam is another substrate for human cytochrome P450-3A isoforms.

21 January 2018

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In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism

21 January 2018

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Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes

21 January 2018

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Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

21 January 2018

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Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

21 January 2018

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Human liver microsomal cytochrome P450 3A isozymes mediated vindesine biotransformation. Metabolic drug interactions

21 January 2018

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21 January 2018

Identifiers

DOI

10.1080/004982599238173

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548453%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

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