The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease (Q92539004)

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30 April 2020

title

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease (English)

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30 April 2020

1

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30 April 2020

Gemma C Monté-Rubio

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Agustín Ruíz

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30 April 2020

Alfredo Ramirez

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Alison Goate

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Miguel Ángel Araque Caballero

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publication date

21 March 2019

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30 April 2020

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Effect of BDNFVal66Met on disease markers in dominantly inherited Alzheimer's disease

30 April 2020

cites work

1 reference

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Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing.

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The Spanish version of Face-Name Associative Memory Exam (S-FNAME) performance is related to amyloid burden in Subjective Cognitive Decline.

11 February 2021

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Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease.

11 February 2021

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Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE).

11 February 2021

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Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study.

11 February 2021

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11 February 2021

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BDNF val66met Polymorphism Impairs Hippocampal Long-Term Depression by Down-Regulation of 5-HT3 Receptors.

11 February 2021

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Functional Connectivity of the Hippocampus in Early- and vs. Late-Onset Alzheimer's Disease

11 February 2021

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The Effect of Aerobic Exercise on Brain-Derived Neurotrophic Factor in People with Neurological Disorders: A Systematic Review and Meta-Analysis

11 February 2021

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BDNF at the synapse: why location matters

11 February 2021

1 reference

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BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF.

11 February 2021

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BDNF Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer's Prevention

11 February 2021

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Phases of Hyperconnectivity and Hypoconnectivity in the Default Mode and Salience Networks Track with Amyloid and Tau in Clinically Normal Individuals

11 February 2021

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Left frontal cortex connectivity underlies cognitive reserve in prodromal Alzheimer disease

11 February 2021

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Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury

11 February 2021

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Cerebrospinal Fluid Aβ42/40 Corresponds Better than Aβ42 to Amyloid PET in Alzheimer's Disease

11 February 2021

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Resting-state global functional connectivity as a biomarker of cognitive reserve in mild cognitive impairment.

11 February 2021

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Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease

11 February 2021

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BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease

11 February 2021

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Enhanced resting-state functional connectivity between core memory-task activation peaks is associated with memory impairment in MCI.

11 February 2021

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11 February 2021

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CSF Aβ42/Aβ40 and Aβ42/Aβ38 ratios: better diagnostic markers of Alzheimer disease

11 February 2021

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Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability

11 February 2021

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Cascading network failure across the Alzheimer's disease spectrum

11 February 2021

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Mapping 3-year changes in gray matter and metabolism in Aβ-positive nondemented subjects

11 February 2021

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Brain-derived neurotrophic factor and TrkB expression in the "oldest-old," the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta

11 February 2021

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Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

11 February 2021

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Long-range neural synchrony in behavior

11 February 2021

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The lower hippocampus global connectivity, the higher its local metabolism in Alzheimer disease

11 February 2021

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APOE and BDNF polymorphisms moderate amyloid β-related cognitive decline in preclinical Alzheimer's disease.

11 February 2021

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Functional connectivity in autosomal dominant and late-onset Alzheimer disease

11 February 2021

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Link between hippocampus' raised local and eased global intrinsic connectivity in AD.

11 February 2021

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The association of the BDNF Val66Met polymorphism and the hippocampal volumes in healthy humans: a joint meta-analysis of published and new data.

11 February 2021

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BDNF and synaptic plasticity, cognitive function, and dysfunction

11 February 2021

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Intrinsic connectivity identifies the hippocampus as a main crossroad between Alzheimer's and semantic dementia-targeted networks

11 February 2021

1 reference

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Effect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer's disease: a preliminary study

11 February 2021

1 reference

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Functional MRI of long-term potentiation: imaging network plasticity.

11 February 2021

1 reference

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Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Cut-off scores of a brief neuropsychological battery (NBACE) for Spanish individual adults older than 44 years old.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Dominantly Inherited Alzheimer Network: facilitating research and clinical trials

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Dissecting the uncinate fasciculus: disorders, controversies and a hypothesis

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

The Evolution of the Wechsler Memory Scale: A Selective Review

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysis.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Comparison of clinical characteristics between familial and non-familial early onset Alzheimer's disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

[Validation of a cognitive complaints questionnaire for young adults: the relation between subjective memory complaints, prefrontal symptoms and perceived stress].

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementias.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Theta oscillations mediate interaction between prefrontal cortex and medial temporal lobe in human memory.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Disturbed functional connectivity within brain networks subserving domain-specific subcomponents of working memory in schizophrenia: relation to performance and clinical symptoms.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Brain-derived neurotrophic factor in neurodegenerative diseases

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Population genetic study of the brain-derived neurotrophic factor (BDNF) gene

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Interactions between medial temporal lobe, prefrontal cortex, and inferior temporal regions during visual working memory: a combined intracranial EEG and functional magnetic resonance imaging study.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

BDNF is essential to promote persistence of long-term memory storage

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Selective changes of resting-state networks in individuals at risk for Alzheimer's disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Reduced hippocampal functional connectivity in Alzheimer disease.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Regionally specific disturbance of dorsolateral prefrontal-hippocampal functional connectivity in schizophrenia.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Comparison of fMRI activation at 3 and 1.5 T during perceptual, cognitive, and affective processing.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Rapid and selective induction of BDNF expression in the hippocampus during contextual learning.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

Topography of the uncinate fascicle and adjacent temporal fiber tracts.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6754794

10.1038/S41380-019-0404-6

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30899092%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30899092%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference