Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein (Q92532340)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

title

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference

0 references

0 references

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Daniel J. Klionsky

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

7

Herbert J Zeh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

author name string

Enyong Dai

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Leng Han

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Jiao Liu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Yangchun Xie

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Rui Kang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Jing Wang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Daolin Tang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

publication date

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

page(s)

1-15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

Understanding the tumor immune microenvironment (TIME) for effective therapy.

30 April 2020

cites work

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

RAS Proteins and Their Regulators in Human Disease

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

RAS oncogenes: weaving a tumorigenic web

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Tumour-associated macrophages as treatment targets in oncology.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Autophagy as a regulated pathway of cellular degradation

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Autophagy and the integrated stress response

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Pancreatic cancers require autophagy for tumor growth

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

p53 status determines the role of autophagy in pancreatic tumour development

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

The receptor RAGE: Bridging inflammation and cancer

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Oxidative Stress: A New Target for Pancreatic Cancer Prognosis and Treatment

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Ageing, oxidative stress and cancer: paradigms in parallax

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

The molecular machinery of regulated cell death

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Ferroptosis is a type of autophagy-dependent cell death

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Diacylglycerol kinase alpha regulates the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Exosomes derived from mesenchymal stem cells enhance radiotherapy-induced cell death in tumor and metastatic tumor foci

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Cytokine-induced release of ceramide-enriched exosomes as a mediator of cell death signaling in an oligodendroglioma cell line

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Exosomes from adipose-derived mesenchymal stem cells prevent cardiomyocyte apoptosis induced by oxidative stress

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Current knowledge on exosome biogenesis and release

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Detection of the receptor for advanced glycation endproducts in neuronally-derived exosomes in plasma.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Hydrogen Peroxide Stimulates Exosomal Cathepsin B Regulation of the Receptor for Advanced Glycation End-Products (RAGE).

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Targeting autophagy in cancer

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Mechanisms and context underlying the role of autophagy in cancer metastasis

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

The role for autophagy in cancer

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

DAMPs, PAMPs and alarmins: all we need to know about danger

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Immunogenic and tolerogenic cell death

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Strange attractors: DAMPs and autophagy link tumor cell death and immunity

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Ferroptosis: process and function

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Ferroptosis: an iron-dependent form of nonapoptotic cell death

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Autophagy promotes ferroptosis by degradation of ferritin

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

BECN1 is a new driver of ferroptosis

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Ferroptosis is a lysosomal cell death process

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

An essential role for functional lysosomes in ferroptosis of cancer cells.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Clockophagy is a novel selective autophagy process favoring ferroptosis

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Autophagic degradation of the circadian clock regulator promotes ferroptosis

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Exosomes in cancer: small vesicular transporters for cancer progression and metastasis, biomarkers in cancer therapeutics.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Exosomes and autophagy: coordinated mechanisms for the maintenance of cellular fitness

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

The interplay between exosomes and autophagy - partners in crime

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Role of receptor for advanced glycation end products (RAGE) and its ligands in cancer risk

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

RAGE maintains high levels of NFκB and oncogenic Kras activity in pancreatic cancer.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

RAGE gene deletion inhibits the development and progression of ductal neoplasia and prolongs survival in a murine model of pancreatic cancer

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

The marine natural product Scalarin inhibits the receptor for advanced glycation end products (RAGE) and autophagy in the PANC-1 and MIA PaCa-2 pancreatic cancer cell lines

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

16 October 2020

Macrophage Polarization.

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Pharmacological targeting of RAS: Recent success with direct inhibitors

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Phase II and pharmacodynamic study of autophagy inhibition using hydroxychloroquine in patients with metastatic pancreatic adenocarcinoma

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Chloroquine and hydroxychloroquine for cancer therapy

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Comparative analysis of exosome isolation methods using culture supernatant for optimum yield, purity and downstream applications

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4.

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Ultracentrifugation versus kit exosome isolation: nanoLC-MS and other tools reveal similar performance biomarkers, but also contaminations

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Novel method for extracting exosomes of hepatocellular carcinoma cells

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Endogenous HMGB1 regulates autophagy

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis

16 October 2020

1 reference

https://api.crossref.org/works/10.1080/15548627.2020.1714209

10.1080/15548627.2020.1714209

16 October 2020

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31920150%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference