Mechanisms underlying aflatoxin-associated mutagenesis - Implications in carcinogenesis (Q92528302)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30897375%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

title

Mechanisms underlying aflatoxin-associated mutagenesis - Implications in carcinogenesis (English)

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30 April 2020

1 reference

Amanda K McCullough

1

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30 April 2020

R Stephen Lloyd

series ordinal

2

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30 April 2020

publication date

7 March 2019

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30 April 2020

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30 April 2020

volume

77

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page(s)

76-86

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Aflatoxin-Guanine DNA Adducts and Oxidatively Induced DNA Damage in Aflatoxin-Treated Mice in Vivo as Measured by Liquid Chromatography-Tandem Mass Spectrometry with Isotope Dilution

30 April 2020

cites work

1 reference

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Impact of DNA lesion repair, replication and formation on the mutational spectra of environmental carcinogens: Aflatoxin B as a case study

11 February 2021

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Qidong hepatitis B virus infection cohort: a 25-year prospective study in high risk area of primary liver cancer

11 February 2021

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The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation.

11 February 2021

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Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver.

11 February 2021

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Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors

11 February 2021

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Aflatoxin B1 exposure increases the risk of cirrhosis and hepatocellular carcinoma in chronic hepatitis B virus carriers

11 February 2021

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Aflatoxin Exposure During Pregnancy, Maternal Anemia, and Adverse Birth Outcomes

11 February 2021

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NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice

11 February 2021

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Genetic Features of Aflatoxin-Associated Hepatocellular Carcinoma.

11 February 2021

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Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma.

11 February 2021

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Profound changes in miRNA expression during cancer initiation by aflatoxin B1 and their abrogation by the chemopreventive triterpenoid CDDO-Im.

11 February 2021

1 reference

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DNA polymerase ζ limits chromosomal damage and promotes cell survival following aflatoxin exposure.

11 February 2021

1 reference

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Hepatocellular carcinoma and hepatitis B surface protein

11 February 2021

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The Polymerase Activity of Mammalian DNA Pol ζ Is Specifically Required for Cell and Embryonic Viability

11 February 2021

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Strategy vaccination against Hepatitis B in China

11 February 2021

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Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

11 February 2021

1 reference

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Prenatal exposure of mice to the human liver carcinogen aflatoxin B1 reveals a critical window of susceptibility to genetic change

11 February 2021

1 reference

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Metabolism of aflatoxins: key enzymes and interindividual as well as interspecies differences

11 February 2021

1 reference

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Reduced foodborne toxin exposure is a benefit of improving dietary diversity

11 February 2021

1 reference

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Error-prone replication bypass of the primary aflatoxin B1 DNA adduct, AFB1-N7-Gua

11 February 2021

1 reference

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Complete protection against aflatoxin B(1)-induced liver cancer with a triterpenoid: DNA adduct dosimetry, molecular signature, and genotoxicity threshold.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Genome-wide and differential proteomic analysis of hepatitis B virus and aflatoxin B1 related hepatocellular carcinoma in Guangxi, China

11 February 2021

1 reference

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Aflatoxins as a cause of hepatocellular carcinoma.

11 February 2021

1 reference

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Reduced aflatoxin exposure presages decline in liver cancer mortality in an endemic region of China

11 February 2021

1 reference

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Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses

11 February 2021

1 reference

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Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities

11 February 2021

1 reference

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Dietary modulation of the biotransformation and genotoxicity of aflatoxin B(1).

11 February 2021

1 reference

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DNA polymerase zeta is required for proliferation of normal mammalian cells

11 February 2021

1 reference

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The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention

11 February 2021

1 reference

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Predictive power of hepatitis B 1762T/1764A mutations in plasma for hepatocellular carcinoma risk in Qidong, China

11 February 2021

1 reference

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Nrf2: control of sensitivity to carcinogens

11 February 2021

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Variable penetrance of metabolic phenotypes and development of high-fat diet-induced adiposity in NEIL1-deficient mice

11 February 2021

1 reference

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Aflatoxin: a 50-year odyssey of mechanistic and translational toxicology

11 February 2021

1 reference

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Polymorphism in xeroderma pigmentosum complementation group C codon 939 and aflatoxin B1-related hepatocellular carcinoma in the Guangxi population.

11 February 2021

1 reference

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Loss of DNA polymerase zeta enhances spontaneous tumorigenesis

11 February 2021

1 reference

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XPD codon 312 and 751 polymorphisms, and AFB1 exposure, and hepatocellular carcinoma risk

11 February 2021

1 reference

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In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Hepatitis B virus infection contributes to oxidative stress in a population exposed to aflatoxin B1 and high-risk for hepatocellular carcinoma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Human polymorphic variants of the NEIL1 DNA glycosylase

11 February 2021

1 reference

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Unraveling the aflatoxin-FAPY conundrum: structural basis for differential replicative processing of isomeric forms of the formamidopyrimidine-type DNA adduct of aflatoxin B1.

11 February 2021

1 reference

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Dominant contribution of P450 3A4 to the hepatic carcinogenic activation of aflatoxin B1.

11 February 2021

1 reference

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The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase

11 February 2021

1 reference

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Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells

11 February 2021

1 reference

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Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes

11 February 2021

1 reference

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Susceptibility to aflatoxin B1-induced carcinogenesis correlates with tissue-specific differences in DNA repair activity in mouse and in rat.

11 February 2021

1 reference

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Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA.

11 February 2021

1 reference

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Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions

11 February 2021

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Immortalized mouse cell lines that lack a functional Rev3 gene are hypersensitive to UV irradiation and cisplatin treatment.

11 February 2021

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Aflatoxin B1 formamidopyrimidine adducts are preferentially repaired by the nucleotide excision repair pathway in vivo

11 February 2021

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The enigma of endonuclease VIII.

11 February 2021

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Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA

11 February 2021

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The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma

11 February 2021

1 reference

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Enhanced spontaneous and aflatoxin-induced liver tumorigenesis in xeroderma pigmentosum group A gene-deficient mice

11 February 2021

1 reference

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Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA

11 February 2021

1 reference

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Interindividual differences in response to chemoprotection against aflatoxin-induced hepatocarcinogenesis: implications for human biotransformation enzyme polymorphisms.

11 February 2021

1 reference

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The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis

11 February 2021

1 reference

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Solution structure of the aminofluorene [AF]-external conformer of the anti-[AF]-C8-dG adduct opposite dC in a DNA duplex.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Species-specific differences in hepatic mutant frequency and mutational spectrum among lambda/lacI transgenic rats and mice following exposure to aflatoxin B1.

11 February 2021

1 reference

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Repair of aflatoxin B1 DNA adducts by the UvrABC endonuclease of Escherichia coli.

11 February 2021

1 reference

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Alterations of tumor suppressor genes and allelic losses in human hepatocellular carcinomas in China

11 February 2021

1 reference

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Procarcinogen activation by cytochrome P450 3A4 and 3A5 expressed in Escherichia coli and by human liver microsomes.

11 February 2021

1 reference

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Temporal patterns of covalent DNA adducts in rat liver after single and multiple doses of aflatoxin B1

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Excision repair of aflatoxin B1-DNA adducts in human fibroblasts

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Excision of aflatoxin B1-imidazole ring opened guanine adducts from DNA by formamidopyrimidine-DNA glycosylase.

11 February 2021

1 reference

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Base substitution mutations induced by metabolically activated aflatoxin B1.

11 February 2021

1 reference

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Aflatoxin B 1 , a hepatocarcinogen in the infant mouse

11 February 2021

1 reference

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Mutational hot spot in the p53 gene in human hepatocellular carcinomas

11 February 2021

1 reference

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p53 mutation in hepatocellular carcinoma after aflatoxin exposure

11 February 2021

1 reference

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Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Sequence specificity of aflatoxin B1-induced mutations in a plasmid replicated in xeroderma pigmentosum and DNA repair proficient human cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

p53 gene mutation spectrum in hepatocellular carcinoma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

p53 Mutations in human hepatocellular carcinomas from Germany

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

p53 mutations cluster at codon 249 in hepatitis B virus-positive hepatocellular carcinomas from China

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Aflatoxin B -oxide generated by chemical or enzymic oxidation of aflatoxin B1 causes guanine substitution in nucleic acids

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6959417

10.1016/J.DNAREP.2019.03.004

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30897375%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30897375%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

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