A3 Adenosine Receptors: Protective vs. Damaging Effects Identified Using Novel Agonists and Antagonists (Q91750595)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31808655%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

title

A3 Adenosine Receptors: Protective vs. Damaging Effects Identified Using Novel Agonists and Antagonists (English)

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24 April 2020

author name string

Kenneth A Jacobson

1

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24 April 2020

Stefano Moro

2

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24 April 2020

Yong-Chul Kim

3

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An-Hu Li

4

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24 April 2020

publication date

1 November 1998

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Drug Development Research

24 April 2020

published in

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volume

45

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issue

3-4

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page(s)

113-124

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Modulation of apoptosis by adenosine in the central nervous system: a possible role for the A3 receptor. Pathophysiological significance and therapeutic implications for neurodegenerative disorders

24 April 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-XL: studies in human astroglioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Selective activation of A3 adenosine receptors with N6-(3-iodobenzyl)adenosine-5'-N-methyluronamide protects against myocardial stunning and infarction without hemodynamic changes in conscious rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5'-N-ethyluronamide as A1 and A3 adenosine receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Adenosine A3 receptors in mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

A functional screening of adenosine analogues at the adenosine A2B receptor: a search for potent agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Adenosine A3 receptors potentiate hippocampal calcium current by a PKA-dependent/PKC-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Mast cell degranulation following adenosine A3 receptor activation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

A3-adenosine receptors: design of selective ligands and therapeutic prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Structure-activity relationships of 4-(phenylethynyl)-6-phenyl-1,4-dihydropyridines as highly selective A3 adenosine receptor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Mutagenesis reveals structure-activity parallels between human A2A adenosine receptors and biogenic amine G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Selective ligands for rat A3 adenosine receptors: structure-activity relationships of 1,3-dialkylxanthine 7-riboside derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Induction of apoptosis in HL-60 human promyelocytic leukemia cells by adenosine A(3) receptor agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

A physiological role of the adenosine A3 receptor: sustained cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Human P2Y1 receptor: molecular modeling and site-directed mutagenesis as tools to identify agonist and antagonist recognition sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Molecular modeling studies of human A3 adenosine antagonists: structural homology and receptor docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Adenosine receptor subtypes: characterization and therapeutic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Differential interaction with and regulation of multiple G-proteins by the rat A3 adenosine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Molecular basis for subtype-specific desensitization of inhibitory adenosine receptors. Analysis of a chimeric A1-A3 adenosine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Activation and Desensitization of Rat A3-Adenosine Receptors by Selective Adenosine Derivatives and Xanthine-7-Ribosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Molecular cloning and characterization of the human A3 adenosine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Adenosine A3 receptor agonist-induced neurotoxicity in rat cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

[125I]4-aminobenzyl-5'-N-methylcarboxamidoadenosine (125I)AB-MECA) labels multiple adenosine receptor subtypes in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Adenosine-induced vasoconstriction in vivo. Role of the mast cell and A3 adenosine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Activation of Phosphoinositide Breakdown and Elevation of Intracellular Calcium in a Rat RBL-2H3 Mast Cell Line by Adenosine Analogs: Involvement of A(3)-Adenosine Receptors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Induction of apoptosis in cardiac myocytes by an A3 adenosine receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Direct preconditioning of cultured chick ventricular myocytes. Novel functions of cardiac adenosine A2a and A3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Selective adenosine A3 receptor stimulation reduces ischemic myocardial injury in the rabbit heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Adenosine A3 receptor stimulation and cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Adenosine A3 receptor expression and function in eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

Adenosine A3 receptor agonists protect HL-60 and U-937 cells from apoptosis induced by A3 antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2299%28199811%2F12%2945%3A3%2F4%3C113%3A%3AAID-DDR5%3E3.0.CO%3B2-S

A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

Protein kinase C and A3 adenosine receptor activation inhibit presynaptic metabotropic glutamate receptor (mGluR) function and uncouple mGluRs from GTP-binding proteins.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

Adenosine A3 receptor stimulation inhibits migration of human eosinophils

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

A novel cardioprotective function of adenosine A1 and A3 receptors during prolonged simulated ischemia

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

Adenosine inhibits neutrophil degranulation in activated human whole blood: involvement of adenosine A2 and A3 receptors

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

Activation of hippocampal adenosine A3 receptors produces a desensitization of A1 receptor-mediated responses in rat hippocampus.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

In vivo role of the adenosine A3 receptor: N6-2-(4-aminophenyl)ethyladenosine induces bronchospasm in BDE rats by a neurally mediated mechanism involving cells resembling mast cells

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

G protein-dependent activation of phospholipase C by adenosine A3 receptors in rat brain

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

Sustained activation of phospholipase D via adenosine A3 receptors is associated with enhancement of antigen- and Ca(2+)-ionophore-induced secretion in a rat mast cell line

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

Molecular cloning and functional expression of a sheep A3 adenosine receptor with widespread tissue distribution.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

Adenosine inhibits the adhesion of anti-CD3-activated killer lymphocytes to adenocarcinoma cells through an A3 receptor

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6893906

10.1002/(SICI)1098-2299(199811/12)45:3/4<113::AID-DDR5>3.0.CO;2-S

23 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31808655%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

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24 April 2020

PubMed publication ID

31808655

1 reference