Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain (Q91675573)

PubMed ID

31043574

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31043574%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

title

Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain (English)

1 reference

PubMed ID

31043574

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31043574%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

1 reference

1

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15 May 2020

Carlo Condello

2

1 reference

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15 May 2020

Weizhou Yue

4

1 reference

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15 May 2020

Brianna M Rivera

5

1 reference

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15 May 2020

Amanda L Woerman

7

1 reference

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15 May 2020

Glenda Halliday

8

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15 May 2020

Sjoerd G van Duinen

9

1 reference

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15 May 2020

Christopher Keene

14

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15 May 2020

William DeGrado

16

1 reference

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15 May 2020

Stanley B. Prusiner

17

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15 May 2020

10

Martin Ingelsson

1 reference

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15 May 2020

11

Lars Lannfelt

1 reference

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15 May 2020

author name string

Jan Stöhr

3

1 reference

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15 May 2020

Joanne C Lee

6

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15 May 2020

Caroline Graff

12

1 reference

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15 May 2020

Thomas D Bird

13

1 reference

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15 May 2020

William W Seeley

15

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15 May 2020

publication date

1 May 2019

1 reference

PubMed ID

31043574

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31043574%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

23 April 2020

published in

1 reference

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15 May 2020

volume

11

1 reference

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15 May 2020

issue

490

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6640844&resulttype=core&format=json

Tau monomer encodes strains

15 May 2020

cites work

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Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation.

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23 February 2021

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23 February 2021

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Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines

23 February 2021

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Fibril structure of amyloid-β(1-42) by cryo-electron microscopy.

23 February 2021

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Prion-like Spreading in Tauopathies

23 February 2021

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Enhanced Tau Aggregation in the Presence of Amyloid β.

23 February 2021

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Apolipoprotein E, Receptors, and Modulation of Alzheimer's Disease

23 February 2021

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Aβ propagation and strains: Implications for the phenotypic diversity in Alzheimer's disease

23 February 2021

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Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease.

23 February 2021

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Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes

23 February 2021

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Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease

23 February 2021

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Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid Samples

23 February 2021

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Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells

23 February 2021

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Widespread tau seeding activity at early Braak stages.

23 February 2021

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Structural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study

23 February 2021

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Neuronal activity enhances tau propagation and tau pathology in vivo.

23 February 2021

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The amyloid cascade hypothesis: are we poised for success or failure?

23 February 2021

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Development of new fusion proteins for visualizing amyloid-β oligomers in vivo

23 February 2021

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Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau.

23 February 2021

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Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

23 February 2021

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Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.

23 February 2021

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Propagation of prions causing synucleinopathies in cultured cells

23 February 2021

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Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections

23 February 2021

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Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

23 February 2021

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Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum

23 February 2021

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Mechanism of scrapie prion precipitation with phosphotungstate anions

23 February 2021

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Progression of Seed-Induced Aβ Deposition within the Limbic Connectome

23 February 2021

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Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis

23 February 2021

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Conformation determines the seeding potencies of native and recombinant Tau aggregates

23 February 2021

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23 February 2021

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23 February 2021

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Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients

23 February 2021

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Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice

23 February 2021

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Distinct tau prion strains propagate in cells and mice and define different tauopathies

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Twenty years of Alzheimer's disease-causing mutations

23 February 2021

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23 February 2021

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23 February 2021

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The Japanese Mutant Aβ (ΔE22-Aβ1−39) Forms Fibrils Instantaneously, with Low-Thioflavin T Fluorescence: Seeding of Wild-Type Aβ1−40into Atypical Fibrils by ΔE22-Aβ1−39

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

23 February 2021

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23 February 2021

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Selective precipitation of prions by polyoxometalate complexes.

23 February 2021

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Glial reactions and the clearance of amyloid beta protein in the brains of patients with hereditary cerebral hemorrhage with amyloidosis-Dutch type

23 February 2021

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23 February 2021

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Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

23 February 2021

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The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

23 February 2021

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Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

23 February 2021

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23 February 2021

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

23 February 2021

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Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala-->Gly mutation.

23 February 2021

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Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

23 February 2021

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Pattern of brain destruction in Parkinson's and Alzheimer's diseases.

23 February 2021

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Frontotemporal dementia and Parkinsonism linked to chromosome 17: a new group of tauopathies.

23 February 2021

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

23 February 2021

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6640844

Neurofibrillary tangles of Alzheimer's disease: an immunohistochemical study

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6640844

Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6640844

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6640844

Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6640844

Filamentous aggregates in Pick's disease, progressive supranuclear palsy, and Alzheimer's disease share antigenic determinants with microtubule-associated protein, tau.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6640844

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6640844

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6640844

10.1126/SCITRANSLMED.AAT8462

23 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6640844&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6640844&resulttype=core&format=json

15 May 2020

1 reference