Lipinski's rule of five (Q916723)
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rule of thumb that a compound is likely orally active if it violates at most one of: ≤5 hydrogen bond donors; ≤10 hydrogen bond acceptors; molecular mass of ≤500 Da; octanol-water partition coefficient of ≤5
- Pfizer's rule of five
- rule of five
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Lipinski's rule of five |
rule of thumb that a compound is likely orally active if it violates at most one of: ≤5 hydrogen bond donors; ≤10 hydrogen bond acceptors; molecular mass of ≤500 Da; octanol-water partition coefficient of ≤5 |
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Statements
1997
0 references
Identifiers
1 reference
Sitelinks
Wikipedia(17 entries)
- arwiki قاعدة ليبينسكي الخمسة
- cawiki Regla del Cinc de Lipinski
- cswiki Lipinského pravidlo
- dewiki Rule of Five
- enwiki Lipinski's rule of five
- eswiki Regla de cinco de Lipinski
- etwiki Lipinski viie reegel
- hewiki כלל החמישה של ליפינסקי
- itwiki Regola di Lipinski
- jawiki リピンスキーの法則
- nlwiki Lipinski's rule of five
- ptwiki Regra dos 5 de lipinski
- ruwiki Правило Липинского
- slwiki Pravilo Lipinskega
- svwiki Lipinskis fem-regel
- ukwiki Правило п'яти
- zhwiki 里宾斯基五规则