Phase II Trial of Ipilimumab with Stereotactic Radiation Therapy for Metastatic Disease: Outcomes, Toxicities, and Low-Dose Radiation-Related Abscopal Responses (Q90974167)

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scientific article published on 28 October 2019

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English	Phase II Trial of Ipilimumab with Stereotactic Radiation Therapy for Metastatic Disease: Outcomes, Toxicities, and Low-Dose Radiation-Related Abscopal Responses	scientific article published on 28 October 2019

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scholarly article

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18 April 2020

Phase II Trial of Ipilimumab with Stereotactic Radiation Therapy for Metastatic Disease: Outcomes, Toxicities, and Low-Dose Radiation-Related Abscopal Responses (English)

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18 April 2020

phase II clinical trial

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based on heuristic

inferred from title

Patricia de Groot

3

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18 April 2020

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18 April 2020

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18 April 2020

James P. Allison

19

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18 April 2020

Maria E Cabanillas

25

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18 April 2020

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18 April 2020

Vassiliki Papadimitrakopoulou

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Vassiliki A Papadimitrakopoulou

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18 April 2020

Erminia Massarelli

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Erminia Massarelli

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18 April 2020

Stephen M. Hahn

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Stephen Hahn

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18 April 2020

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James W Welsh

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18 April 2020

Chad Tang

2

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18 April 2020

Kenneth R Hess

5

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18 April 2020

Taylor R Cushman

8

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18 April 2020

Vivek Subbiah

9

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18 April 2020

Joe Y Chang

10

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18 April 2020

George R Simon

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18 April 2020

Rishab Ramapriyan

12

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18 April 2020

Hampartsoum B Barsoumian

13

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18 April 2020

Hari Menon

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18 April 2020

Maria Angelica Cortez

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18 April 2020

Quynh Nguyen

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18 April 2020

Padmanee Sharma

18

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18 April 2020

Adi Diab

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18 April 2020

Vivek Verma

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18 April 2020

Uma Raju

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18 April 2020

Sherif G Shaaban

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18 April 2020

Ramona Dadu

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18 April 2020

Kelvin Wang

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18 April 2020

Clark Anderson

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18 April 2020

Daniel R Gomez

28

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18 April 2020

Ritsuko Komaki

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18 April 2020

publication date

28 October 2019

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18 April 2020

Cancer Immunology Research

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18 April 2020

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18 April 2020

12

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18 April 2020

1903-1909

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18 April 2020

Safety of Combined Immunotherapy and Thoracic Radiation Therapy: Analysis of 3 Single-Institutional Phase I/II Trials

1 reference

12 October 2022

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Ipilimumab with Stereotactic Ablative Radiation Therapy: Phase I Results and Immunologic Correlates from Peripheral T Cells

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12 October 2022

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Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer

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DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

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12 October 2022

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Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

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Radiotherapy induces responses of lung cancer to CTLA-4 blockade

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The role of low-dose total body irradiation in treatment of non-Hodgkin's lymphoma: a new look at an old method.

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Stereotactic ablative radiation therapy for centrally located early stage or isolated parenchymal recurrences of non-small cell lung cancer: how to fly in a "no fly zone".

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Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions

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Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

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12 October 2022

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Beneficial effects of low dose radiation in response to the oncogenic KRAS induced cellular transformation

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Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti-PD-1 treatment.

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Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.

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Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria

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Immune effects of low-dose radiation: short-term induction of thymocyte apoptosis and long-term augmentation of T-cell-dependent immune responses

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Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

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Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy

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Identifiers

10.1158/2326-6066.CIR-18-0793

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31658994%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31658994%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

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