Differential Roles of Each Orexin Receptor Signaling in Obesity (Q90220749)

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12 April 2020

title

Differential Roles of Each Orexin Receptor Signaling in Obesity (English)

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12 April 2020

4

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Hiromasa Funato

10

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12 April 2020

author name string

Miyo Kakizaki

1

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12 April 2020

Yousuke Tsuneoka

2

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12 April 2020

Kenkichi Takase

3

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12 April 2020

Jinhwan Choi

5

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12 April 2020

Aya Ikkyu

6

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12 April 2020

Manabu Abe

7

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Kenji Sakimura

8

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Masashi Yanagisawa

9

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publication date

9 September 2019

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12 April 2020

volume

20

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12 April 2020

page(s)

1-13

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Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

12 April 2020

cites work

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12 December 2020

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

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12 December 2020

Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight

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12 December 2020

Orexin synthesis and response in the gut.

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12 December 2020

A selective orexin-1 receptor antagonist reduces food consumption in male and female rats.

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12 December 2020

SB-334867, a selective orexin-1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin-A in rats

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12 December 2020

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

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12 December 2020

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

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12 December 2020

Genetic vulnerability to diet-induced obesity in the C57BL/6J mouse: physiological and molecular characteristics

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12 December 2020

Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions.

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12 December 2020

Evidence that orexins A and B stimulate insulin secretion from rat pancreatic islets via both receptor subtypes

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12 December 2020

The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness

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12 December 2020

Clinical and neurobiological aspects of narcolepsy

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12 December 2020

Differential effects of the hypocretin 1 receptor antagonist SB 334867 on high-fat food self-administration and reinstatement of food seeking in rats

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12 December 2020

Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity

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12 December 2020

Orexin A/hypocretin-1 selectively promotes motivation for positive reinforcers

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12 December 2020

Orexin-1 receptor co-localizes with pancreatic hormones in islet cells and modulates the outcome of streptozotocin-induced diabetes mellitus

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12 December 2020

Orexin signaling via the orexin 1 receptor mediates operant responding for food reinforcement.

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12 December 2020

Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

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12 December 2020

Orexin/hypocretin modulates response of ventral tegmental dopamine neurons to prefrontal activation: diurnal influences.

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12 December 2020

Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal

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12 December 2020

Orexin is required for brown adipose tissue development, differentiation, and function

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12 December 2020

Bmal1 in the nervous system is essential for normal adaptation of circadian locomotor activity and food intake to periodic feeding.

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12 December 2020

An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesis

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12 December 2020

Role of orexin-1 receptor mechanisms on compulsive food consumption in a model of binge eating in female rats

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12 December 2020

Orexin receptors: multi-functional therapeutic targets for sleeping disorders, eating disorders, drug addiction, cancers and other physiological disorders

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12 December 2020

Orexin restores aging-related brown adipose tissue dysfunction in male mice.

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12 December 2020

Orexin neurons suppress narcolepsy via 2 distinct efferent pathways

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12 December 2020

The selective orexin receptor 1 antagonist ACT-335827 in a rat model of diet-induced obesity associated with metabolic syndrome

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12 December 2020

Acute high fat diet consumption activates the mesolimbic circuit and requires orexin signaling in a mouse model

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12 December 2020

Orexin regulates bone remodeling via a dominant positive central action and a subordinate negative peripheral action

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12 December 2020

Binge-like consumption of caloric and non-caloric palatable substances in ad libitum-fed C57BL/6J mice: pharmacological and molecular evidence of orexin involvement.

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12 December 2020

Orexin/hypocretin activates mTOR complex 1 (mTORC1) via an Erk/Akt-independent and calcium-stimulated lysosome v-ATPase pathway.

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12 December 2020

The role of orexin in motivated behaviours

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12 December 2020

Hypocretin/Orexin regulation of dopamine signaling and cocaine self-administration is mediated predominantly by hypocretin receptor 1.

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12 December 2020

Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists.

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12 December 2020

A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.

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12 December 2020

A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance.

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12 December 2020

Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice.

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12 December 2020

The Discovery of Suvorexant, the First Orexin Receptor Drug for Insomnia.

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12 December 2020

Mechanisms, Pathophysiology, and Management of Obesity

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12 December 2020

mTOR Signaling in Growth, Metabolism, and Disease.

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12 December 2020

The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases.

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12 December 2020

An Update on Dual Orexin Receptor Antagonists and Their Potential Role in Insomnia Therapeutics.

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12 December 2020

The neurobiological basis of narcolepsy

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12 December 2020

Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier

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12 December 2020

10.1016/J.ISCI.2019.09.003

Identifiers

DOI

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