PD-L1 (CD274) promoter methylation predicts survival in patients with acute myeloid leukemia (Q88754466)

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27 March 2020

title

PD-L1 (CD274) promoter methylation predicts survival in patients with acute myeloid leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27840427%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

main subject

acute myeloid leukemia

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D Goltz

1

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27 March 2020

H Gevensleben

2

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27 March 2020

S Grünen

3

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27 March 2020

J Dietrich

4

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27 March 2020

G Kristiansen

5

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27 March 2020

J Landsberg

6

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27 March 2020

D Dietrich

7

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publication date

14 November 2016

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27 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27840427%20AND%20SRC:MED&resulttype=core&format=json

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volume

31

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issue

3

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page(s)

738-743

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Survival and cure of acute myeloid leukaemia in England, 1971-2006: a population-based study

27 March 2020

cites work

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Harnessing the immune system in acute myeloid leukaemia

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Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

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Myeloid leukemia cells with a B7-2(+) subpopulation provoke Th-cell responses and become immuno-suppressive through the modulation of B7 ligands.

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7 January 2021

In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis.

1 reference

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7 January 2021

Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia

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7 January 2021

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.328

7 January 2021

Expression of PD-L1, PD-L2, PD-1 and CTLA4 in myelodysplastic syndromes is enhanced by treatment with hypomethylating agents.

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7 January 2021

Regulation of PD-L1: a novel role of pro-survival signalling in cancer.

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7 January 2021

Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.

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7 January 2021

Treg cell function in rheumatoid arthritis is compromised by ctla-4 promoter methylation resulting in a failure to activate the indoleamine 2,3-dioxygenase pathway.

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7 January 2021

Functions of DNA methylation: islands, start sites, gene bodies and beyond

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7 January 2021

CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells.

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7 January 2021

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

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7 January 2021

Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies

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7 January 2021

Identifiers

DOI

10.1038/LEU.2016.328

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27840427%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

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