The proinflammatory protein HMGB1 is a substrate of transglutaminase-2 and forms high-molecular weight complexes with autoantigens (Q88268018)

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22 March 2020

title

The proinflammatory protein HMGB1 is a substrate of transglutaminase-2 and forms high-molecular weight complexes with autoantigens (English)

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22 March 2020

author name string

William L Willis

1

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22 March 2020

Linan Wang

2

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22 March 2020

Takuma Tsuzuki Wada

3

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22 March 2020

Mark Gardner

4

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22 March 2020

Omar Abdouni

5

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22 March 2020

Jeffrey Hampton

6

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22 March 2020

Giancarlo Valiente

7

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22 March 2020

Nicholas Young

8

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22 March 2020

Stacy Ardoin

9

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22 March 2020

Sudha Agarwal

10

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22 March 2020

Michael A Freitas

11

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22 March 2020

Lai-Chu Wu

12

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22 March 2020

Wael N Jarjour

13

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22 March 2020

language of work or name

English

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publication date

4 April 2018

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Journal of Biological Chemistry

22 March 2020

published in

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22 March 2020

volume

293

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22 March 2020

issue

22

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22 March 2020

page(s)

8394-8409

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describes a project that uses

22 March 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

The epsilon-(gamma-glutamyl)lysine crosslink and the catalytic role of transglutaminases

1 reference

12 December 2020

Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action

1 reference

12 December 2020

Do naturally occurring autoantibodies participate in the constitution of the pathological B-cell repertoire in systemic lupus erythematosus?

1 reference

12 December 2020

Role of calcium in tumor necrosis factor-alpha production by activated macrophages

1 reference

12 December 2020

Increase in transglutaminase and its extracellular products in response to an inflammatory stimulus by lipopolysaccharide

1 reference

12 December 2020

Identification of tissue transglutaminase as the autoantigen of celiac disease

1 reference

12 December 2020

Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

1 reference

12 December 2020

Autoantibodies against cytoskeletal proteins in rheumatoid arthritis

1 reference

12 December 2020

The autoantibody repertoire: searching for order

1 reference

12 December 2020

Analysis of transglutaminase protein substrates by functional proteomics.

1 reference

12 December 2020

Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells

1 reference

12 December 2020

Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

1 reference

12 December 2020

Molecular characterization of covalent complexes between tissue transglutaminase and gliadin peptides

1 reference

12 December 2020

HMGB1 is an endogenous immune adjuvant released by necrotic cells

1 reference

12 December 2020

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

1 reference

12 December 2020

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

1 reference

12 December 2020

Reciprocal regulation of nuclear factor kappa B and its inhibitor ZAS3 after peripheral nerve injury

1 reference

12 December 2020

Lack of 'tissue' transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLIpr/Ipr mice.

1 reference

12 December 2020

Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathway

1 reference

12 December 2020

Analysis of amyloid aggregates using agarose gel electrophoresis

1 reference

12 December 2020

Factors masking HMGB1 in human serum and plasma

1 reference

12 December 2020

Nucleocytoplasmic shuttling of HMGB1 is regulated by phosphorylation that redirects it toward secretion

1 reference

12 December 2020

Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1

1 reference

12 December 2020

The role of chaperone proteins in autoimmunity.

1 reference

12 December 2020

Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

1 reference

12 December 2020

Apoptotic cell clearance and autoimmune disorder

1 reference

12 December 2020

HMGB1 develops enhanced proinflammatory activity by binding to cytokines.

1 reference

12 December 2020

Transglutaminase type II is involved in the pathogenesis of endotoxic shock

1 reference

12 December 2020

High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes.

1 reference

12 December 2020

Expression of high mobility group protein 1 in the sera of patients and mice with systemic lupus erythematosus

1 reference

12 December 2020

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

1 reference

12 December 2020

The propensity for deamidation and transamidation of peptides by transglutaminase 2 is dependent on substrate affinity and reaction conditions

1 reference

12 December 2020

Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE

1 reference

12 December 2020

Screening for amyloid aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis

1 reference

12 December 2020

MassMatrix: a database search program for rapid characterization of proteins and peptides from tandem mass spectrometry data

1 reference

12 December 2020

1 reference

12 December 2020

Co-immunization with an optimized plasmid-encoded immune stimulatory interleukin, high-mobility group box 1 protein, results in enhanced interferon-gamma secretion by antigen-specific CD8 T cells

1 reference

12 December 2020

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

1 reference

12 December 2020

Expression of high mobility group box chromosomal protein 1 and its modulating effects on downstream cytokines in systemic lupus erythematosus.

1 reference

12 December 2020

HMGB proteins and transcriptional regulation

1 reference

12 December 2020

Database search algorithm for identification of intact cross-links in proteins and peptides using tandem mass spectrometry.

1 reference

12 December 2020

HMGB1 in systemic lupus Erythematosus: Its role in cutaneous lesions development

1 reference

12 December 2020

Redox regulation of transglutaminase 2 activity

1 reference

12 December 2020

Endogenous HMGB1 regulates autophagy

1 reference

12 December 2020

High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activity

1 reference

12 December 2020

High-mobility group box 1, oxidative stress, and disease

1 reference

12 December 2020

Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-α and TNF-α in systemic lupus erythematosus

1 reference

12 December 2020

Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination

1 reference

12 December 2020

High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts.

1 reference

12 December 2020

Transglutaminase 2: a molecular Swiss army knife

1 reference

12 December 2020

New insights into the functions and localization of nuclear transglutaminase 2.

1 reference

12 December 2020

High mobility group box protein 1 (HMGB1)-partner molecule complexes enhance cytokine production by signaling through the partner molecule receptor

1 reference

12 December 2020

HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease

1 reference

12 December 2020

Novel estrogen target gene ZAS3 is overexpressed in systemic lupus erythematosus

1 reference

12 December 2020

Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation

1 reference

12 December 2020

The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

1 reference

12 December 2020

Transglutaminase-2 mediates calcium-regulated crosslinking of the Y-box 1 (YB-1) translation-regulatory protein in TGFβ1-activated myofibroblasts.

1 reference

12 December 2020

Enhanced B-Cell Receptor Recognition of the Autoantigen Transglutaminase 2 by Efficient Catalytic Self-Multimerization

1 reference

12 December 2020

Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage

1 reference

12 December 2020

Ethyl pyruvate inhibits the acetylation and release of HMGB1 via effects on SIRT1/STAT signaling in LPS-activated RAW264.7 cells and peritoneal macrophages

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.RA117.001078

1 reference

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22 March 2020

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22 March 2020

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