α-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies-Part 1 (Q88072959)

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20 March 2020

title

α-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies-Part 1 (English)

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20 March 2020

author name string

Sophie Poty

1

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20 March 2020

Lynn C Francesconi

2

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20 March 2020

Michael R McDevitt

3

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20 March 2020

Michael J Morris

4

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20 March 2020

Jason S Lewis

5

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20 March 2020

language of work or name

English

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publication date

15 March 2018

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The Journal of Nuclear Medicine

20 March 2020

published in

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20 March 2020

volume

59

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20 March 2020

issue

6

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20 March 2020

page(s)

878-884

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224Ra: risk to bone and haematopoietic tissue in ankylosing spondylitis patients

20 March 2020

cites work

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12 December 2020

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12 December 2020

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Survival of human lung epithelial cells following in vitro alpha-particle irradiation with absolute determination of the number of alpha-particle traversals of individual cells

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A 212Pb generator based on a 228Th source

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Radiation risk to low fluences of alpha particles may be greater than we thought

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Design and synthesis of 225Ac radioimmunopharmaceuticals

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Pretargeted alpha emitting radioimmunotherapy using (213)Bi 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid-biotin

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12 December 2020

227Th-EDTMP: a potential therapeutic agent for bone metastasis

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12 December 2020

Production of actinium-225 for alpha particle mediated radioimmunotherapy.

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Efforts to control the errant products of a targeted in vivo generator

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12 December 2020

Initial evaluation of (227)Th-p-benzyl-DOTA-rituximab for low-dose rate alpha-particle radioimmunotherapy.

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12 December 2020

Radiotoxicity of the alpha-emitting bone-seeker 223Ra injected intravenously into mice: histology, clinical chemistry and hematology.

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First in vivo evaluation of liposome-encapsulated 223Ra as a potential alpha-particle-emitting cancer therapeutic agent

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Treatment of solid tumors by interstitial release of recoiling short-lived alpha emitters

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Malignant transformation of human benign prostate epithelial cells by high linear energy transfer alpha-particles.

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Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6

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Cancer Imaging and Therapy with Bispecific Antibody Pretargeting

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Realizing the potential of the Actinium-225 radionuclide generator in targeted alpha particle therapy applications

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Consequences of cytoplasmic irradiation: studies from microbeam

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MIRD Pamphlet No. 22 (abridged): radiobiology and dosimetry of alpha-particle emitters for targeted radionuclide therapy.

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Astatine Radiopharmaceuticals: Prospects and Problems

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Renal uptake of bismuth-213 and its contribution to kidney radiation dose following administration of actinium-225-labeled antibody.

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Towards translation of 212Pb as a clinical therapeutic; getting the lead in!

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Astatine-211: production and availability

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Production of [(211)At]-astatinated radiopharmaceuticals and applications in targeted α-particle therapy

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Intratumoral 224Ra-loaded wires spread alpha-emitters inside solid human tumors in athymic mice achieving tumor control.

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Molecular pathways: targeted α-particle radiation therapy

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12 December 2020

Comparison of 211At-PRIT and 211At-RIT of ovarian microtumors in a nude mouse model

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Gold coated lanthanide phosphate nanoparticles for targeted alpha generator radiotherapy

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12 December 2020

Methodology for labeling proteins and peptides with lead-212 (212Pb)

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12 December 2020

Phase I pharmacokinetic and biodistribution study with escalating doses of ²²³Ra-dichloride in men with castration-resistant metastatic prostate cancer.

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Alpha-particle emitting 213Bi-anti-EGFR immunoconjugates eradicate tumor cells independent of oxygenation

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Radiation safety considerations for the use of ²²³RaCl₂ DE in men with castration-resistant prostate cancer

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Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy

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Antitumor immunity induced after α irradiation

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Efficient 1-step radiolabeling of monoclonal antibodies to high specific activity with 225Ac for α-particle radioimmunotherapy of cancer

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A nuclear chocolate box: the periodic table of nuclear medicine.

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A Critical Review of Alpha Radionuclide Therapy-How to Deal with Recoiling Daughters?

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Vascular Targeted Radioimmunotherapy for the Treatment of Glioblastoma

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12 December 2020

Remodeling the Vascular Microenvironment of Glioblastoma with α-Particles

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225Ac-PSMA-617 for PSMA-Targeted α-Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer.

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12 December 2020

An efficient chelator for complexation of thorium-227.

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12 December 2020

Large scale accelerator production of 225Ac: Effective cross sections for 78-192MeV protons incident on 232Th targets.

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12 December 2020

Evaluation of the separation and purification of 227Th from its decay progeny by anion exchange and extraction chromatography

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12 December 2020

The Future of Radioligand Therapy: α, β, or Both?

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12 December 2020

Pretargeted Imaging and Therapy

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12 December 2020

10.2967/JNUMED.116.186338

Identifiers

DOI

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20 March 2020

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20 March 2020

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