Rational design of multiple TB antigens TB10.4 and TB10.4-Ag85B as subunit vaccine candidates against Mycobacterium tuberculosis (Q84796471)

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11 February 2020

title

Rational design of multiple TB antigens TB10.4 and TB10.4-Ag85B as subunit vaccine candidates against Mycobacterium tuberculosis (English)

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11 February 2020

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Mycobacterium tuberculosis

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Shuai Shi

1

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11 February 2020

Lan Yu

2

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11 February 2020

Dengyun Sun

3

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11 February 2020

Jian Liu

4

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11 February 2020

Anthony J Hickey

5

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11 February 2020

publication date

28 October 2009

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11 February 2020

published in

Pharmaceutical Research

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11 February 2020

volume

27

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issue

2

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page(s)

224-234

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Oligomerization endows enormous stability to soybean agglutinin: a comparison of the stability of monomer and tetramer of soybean agglutinin

11 February 2020

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Efficacy of recombinant anthrax vaccine against Bacillus anthracis aerosol spore challenge: preclinical evaluation in rabbits and Rhesus monkeys

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Variation in protection by BCG: implications of and for heterologous immunity

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Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6

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Efficacious recombinant influenza vaccines produced by high yield bacterial expression: a solution to global pandemic and seasonal needs.

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Tuberculosis: latency and reactivation

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Comparative evaluation of low-molecular-mass proteins from Mycobacterium tuberculosis identifies members of the ESAT-6 family as immunodominant T-cell antigens

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The efficacy of bacillus Calmette-Guérin vaccination of newborns and infants in the prevention of tuberculosis: meta-analyses of the published literature

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Protein conformation significantly influences immune responses to prion protein.

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Protein refolding for industrial processes

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IS6110 mediates increased transcription of the phoP virulence gene in a multidrug-resistant clinical isolate responsible for tuberculosis outbreaks

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Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds.

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A new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosis

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Effect of BCG revaccination on incidence of tuberculosis in school-aged children in Brazil: the BCG-REVAC cluster-randomised trial

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Novel replication-incompetent adenoviral B-group vectors: high vector stability and yield in PER.C6 cells

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Poly (lactide-co-glycolide) microspheres in respirable sizes enhance an in vitro T cell response to recombinant Mycobacterium tuberculosis antigen 85B.

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12 December 2020

Epitope mapping of the immunodominant antigen TB10.4 and the two homologous proteins TB10.3 and TB12.9, which constitute a subfamily of the esat-6 gene family

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Recombinant bacillus calmette-guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model

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12 December 2020

The thioredoxin system: a key target in tumour and endothelial cells

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12 December 2020

Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of antigen 85b and esat-6.

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12 December 2020

A thioredoxin gene fusion expression system that circumvents inclusion body formation in the E. coli cytoplasm.

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12 December 2020

Recombinant protein folding and misfolding in Escherichia coli

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12 December 2020

Areas of adhesion between wall and membrane of Escherichia coli.

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12 December 2020

Does the efficacy of BCG decline with time since vaccination?

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12 December 2020

Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature

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12 December 2020

The mycobacterial antigens 85 complex - from structure to function and beyond

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12 December 2020

T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups

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12 December 2020

Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy

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12 December 2020

10.1007/S11095-009-9995-Y

Identifiers

DOI

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11 February 2020

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