RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients (Q84744537)

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10 February 2020

title

RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients (English)

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10 February 2020

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Jörg-Christian Heinrich

1

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10 February 2020

Anne Tuukkanen

2

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10 February 2020

Michael Schroeder

3

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10 February 2020

Torsten Fahrig

4

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10 February 2020

Rudolf Fahrig

5

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10 February 2020

publication date

22 July 2011

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Journal of Cancer Research and Clinical Oncology

10 February 2020

published in

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volume

137

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10 February 2020

page(s)

1349-1361

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10 February 2020

issue

9

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https://scigraph.springernature.com/pub.10.1007/s00432-011-1005-1

10 February 2020

exact match

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cites work

Deoxyribonucleic acid damage induced by doxorubicin in peripheral blood mononuclear cells: possible roles for the stress response and the deoxyribonucleic acid repair process

1 reference

12 December 2020

Hsp27 overexpression inhibits doxorubicin-induced apoptosis in human breast cancer cells.

1 reference

12 December 2020

Crystal structure of poxvirus thymidylate kinase: An unexpected dimerization has implications for antiviral therapy

1 reference

12 December 2020

Crystal structure of varicella zoster virus thymidine kinase

1 reference

12 December 2020

HSP27 and cell death in spinocerebellar ataxia type 3.

1 reference

12 December 2020

Heat-shock proteins associated with base excision repair enzymes in HeLa cells.

1 reference

12 December 2020

Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

1 reference

12 December 2020

Upregulated HSP27 in human breast cancer cells reduces Herceptin susceptibility by increasing Her2 protein stability

1 reference

12 December 2020

Increased Hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3-mediated suppression of apoptosis

1 reference

12 December 2020

SAM-T08, HMM-based protein structure prediction.

1 reference

12 December 2020

Heat-shock protein 27: a potential biomarker for hepatocellular carcinoma identified by serum proteome analysis

1 reference

12 December 2020

Expression of heat shock protein 27 and alpha-crystallins in human retinoblastoma after chemoreduction

1 reference

12 December 2020

Inhibition of induced chemoresistance by cotreatment with (E)-5-(2-bromovinyl)-2'-deoxyuridine (RP101).

1 reference

12 December 2020

Current approaches and future strategies for pancreatic carcinoma

1 reference

12 December 2020

Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands

1 reference

12 December 2020

Metastatic pancreatic cancer: is gemcitabine still the best standard treatment? (Review).

1 reference

12 December 2020

Current standards of surgery for pancreatic cancer.

1 reference

12 December 2020

Small interference RNA targeting heat-shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase-3 activation in vitro

1 reference

12 December 2020

Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells

1 reference

12 December 2020

Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy.

1 reference

12 December 2020

Novel triazole ribonucleoside down-regulates heat shock protein 27 and induces potent anticancer activity on drug-resistant pancreatic cancer.

1 reference

12 December 2020

1 reference

12 December 2020

Prevention of adriamycin-induced mdr1 gene amplification and expression in mouse leukemia cells by simultaneous treatment with the anti-recombinogen bromovinyldeoxyuridine.

1 reference

12 December 2020

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1 reference

12 December 2020

Proteomics finding heat shock protein 27 as a biomarker for resistance of pancreatic cancer cells to gemcitabine.

1 reference

12 December 2020

Overexpression of 27-kDa heat-shock protein in MCF-7 breast cancer cells: effects on lymphocyte-mediated killing by natural killer and gamma delta T cells

1 reference

12 December 2020

Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties

1 reference

12 December 2020

Scalable molecular dynamics with NAMD

1 reference

12 December 2020

Differential proteomic analysis of human colorectal carcinoma cell lines metastasis-associated proteins

1 reference

12 December 2020

RP101 improves the efficacy of chemotherapy in pancreas carcinoma cell lines and pancreatic cancer patients

1 reference

12 December 2020

HSP27 regulates cell adhesion and invasion via modulation of focal adhesion kinase and MMP-2 expression

1 reference

12 December 2020

Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma

1 reference

12 December 2020

Hsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets.

1 reference

12 December 2020

Hsp27 protects adenocarcinoma cells from UV-induced apoptosis by Akt and p21-dependent pathways of survival

1 reference

12 December 2020

Stat3 modulates heat shock 27kDa protein expression in breast epithelial cells

1 reference

12 December 2020

Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3.

1 reference

12 December 2020

Heat Shock Protein 27 Controls Apoptosis by Regulating Akt Activation

1 reference

12 December 2020

Anti-recombinogenic and convertible co-mutagenic effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and other 5-substituted pyrimidine nucleoside analogs in S. cerevisiae MP1.

1 reference

12 December 2020

Mechanisms of multidrug resistance in cancer treatment

1 reference

12 December 2020

LIGSITEcsc: predicting ligand binding sites using the Connolly surface and degree of conservation

1 reference

12 December 2020

Heat-shock proteins protect cells from monocyte cytotoxicity: possible mechanism of self-protection

1 reference

12 December 2020

A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer

1 reference

12 December 2020

Targeting DNA topoisomerase II in cancer chemotherapy

1 reference

12 December 2020

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1 reference

12 December 2020

Cancer statistics, 2007

1 reference

12 December 2020

Altered expression of anti-apoptotic proteins in non-involved tissue from cancer-containing breasts

1 reference

12 December 2020

10.1007/S00432-011-1005-1

Identifiers

DOI

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10 February 2020

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