Single intravenous low-dose injections of connexin 43 mimetic peptides protect ischemic heart in vivo against myocardial infarction (Q84650485)

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9 February 2020

title

Single intravenous low-dose injections of connexin 43 mimetic peptides protect ischemic heart in vivo against myocardial infarction (English)

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9 February 2020

main subject

myocardial infarction

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Ghayda Hawat

1

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9 February 2020

Pierre Hélie

series ordinal

2

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9 February 2020

Ghayath Baroudi

series ordinal

3

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9 February 2020

publication date

27 July 2012

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841862%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular and Cellular Cardiology

9 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841862%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

53

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9 February 2020

page(s)

559-566

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9 February 2020

issue

4

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Gating and regulation of connexin 43 (Cx43) hemichannels

9 February 2020

cites work

1 reference

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Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

7 January 2021

1 reference

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Connexin-43 hemichannels opened by metabolic inhibition

7 January 2021

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Metabolic inhibition activates a non-selective current through connexin hemichannels in isolated ventricular myocytes.

7 January 2021

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Activation of connexin-43 hemichannels can elevate [Ca(2+)]i and [Na(+)]i in rabbit ventricular myocytes during metabolic inhibition

7 January 2021

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Physiological role of gap-junctional hemichannels. Extracellular calcium-dependent isosmotic volume regulation

7 January 2021

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ATP release by cardiac myocytes in a simulated ischaemia model: inhibition by a connexin mimetic and enhancement by an antiarrhythmic peptide

7 January 2021

1 reference

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ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function

7 January 2021

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Myocardial potassium loss and cell depolarisation in ischaemia and hypoxia

7 January 2021

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Volume regulation and plasma membrane injury in aerobic, anaerobic, and ischemic myocardium in vitro. Effects of osmotic cell swelling on plasma membrane integrity.

7 January 2021

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Hemichannels in cardiomyocytes open transiently during ischemia and contribute to reperfusion injury following brief ischemia

7 January 2021

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Gap junction uncoupler heptanol prevents cell-to-cell progression of hypercontracture and limits necrosis during myocardial reperfusion

7 January 2021

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Gap junction uncoupling protects the heart against ischemia

7 January 2021

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Gap junction-mediated spread of cell injury and death during myocardial ischemia-reperfusion.

7 January 2021

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Connexin43 as a determinant of myocardial infarct size following coronary occlusion in mice

7 January 2021

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Effects of substitution of Cx43 by Cx32 on myocardial energy metabolism, tolerance to ischaemia and preconditioning protection.

7 January 2021

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Hemichannels in cerebral ischemia

7 January 2021

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Cell membrane permeabilization via connexin hemichannels in living and dying cells

7 January 2021

1 reference

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Connexin 43 mimetic peptide Gap26 confers protection to intact heart against myocardial ischemia injury

7 January 2021

1 reference

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Role of connexin 43 in ischemic preconditioning does not involve intercellular communication through gap junctions.

7 January 2021

1 reference

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Protection afforded by ischemic preconditioning is not mediated by effects on cell-to-cell electrical coupling during myocardial ischemia-reperfusion

7 January 2021

1 reference

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Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26.

7 January 2021

1 reference

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Connexin channels, connexin mimetic peptides and ATP release

7 January 2021

1 reference

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Gap junction-mimetic peptides do work, but in unexpected ways

7 January 2021

1 reference

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Novel mechanism for Brugada syndrome: defective surface localization of an SCN5A mutant (R1432G).

7 January 2021

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Differential modulation of unapposed connexin 43 hemichannel electrical conductance by protein kinase C isoforms

7 January 2021

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Gap junction reduction in cardiomyocytes following transforming growth factor-beta treatment and Trypanosoma cruzi infection

7 January 2021

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Pathological remodeling of cardiac gap junction connexin 43-With special reference to arrhythmogenesis

7 January 2021

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Life cycle of connexins: regulation of connexin synthesis and degradation

7 January 2021

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Presence of connexin 43 in subsarcolemmal, but not in interfibrillar cardiomyocyte mitochondria.

7 January 2021

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Pretreatment with D-myo-inositol trisphosphate reduces infarct size in rabbit hearts: role of inositol trisphosphate receptors and gap junctions in triggering protection

7 January 2021

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Factors affecting drug and gene delivery: effects of interaction with blood components

7 January 2021

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Comparison of buffer and red blood cell perfusion of guinea pig heart oxygenation.

7 January 2021

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The gap junction cellular internet: connexin hemichannels enter the signalling limelight

7 January 2021

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Perturbing plasma membrane hemichannels attenuates calcium signalling in cardiac cells and HeLa cells expressing connexins

7 January 2021

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Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning

7 January 2021

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Connexin 43 in ischemic pre- and postconditioning.

7 January 2021

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New, emerging roles for cardiac connexins. Mitochondrial Cx43 raises new questions

7 January 2021

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Mitochondrial connexin43 as a new player in the pathophysiology of myocardial ischaemia-reperfusion injury.

7 January 2021

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Reperfusion injury induces apoptosis in rabbit cardiomyocytes

7 January 2021

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Reperfusion induces myocardial apoptotic cell death

7 January 2021

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10.1016/J.YJMCC.2012.07.008

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841862%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference