Promoting angiogenesis within the tumor microenvironment: the secret life of murine lymphoid IL-17-producing gammadelta T cells (Q84409413)

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5 February 2020

title

Promoting angiogenesis within the tumor microenvironment: the secret life of murine lymphoid IL-17-producing gammadelta T cells (English)

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1

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publication date

1 July 2010

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European Journal of Immunology

5 February 2020

published in

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volume

40

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issue

7

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page(s)

1873-1876

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Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

5 February 2020

cites work

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CD4+ T cell--mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells.

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Interleukin-17 promotes angiogenesis and tumor growth

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IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells

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T helper 17 cells promote cytotoxic T cell activation in tumor immunity

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Tumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor by promoting angiogenesis

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CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets

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Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism

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Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma

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In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells

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7 January 2021

Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers.

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Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

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7 January 2021

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

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7 January 2021

Inhibition of murine gammadelta lymphocyte expansion and effector function by regulatory alphabeta T cells is cell-contact-dependent and sensitive to GITR modulation

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7 January 2021

Neonates harbour highly active gammadelta T cells with selective impairments in preterm infants.

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7 January 2021

Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells

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7 January 2021

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IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis

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7 January 2021

IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

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7 January 2021

Identifiers

DOI

10.1002/EJI.201040707

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20549671%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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