Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas (Q82297408)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Murray O. Robinson

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

12

Tyler Jacks

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Yinghui Zhou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

William M Rideout

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Tong Zi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Angela Bressel

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Shailaja Reddypalli

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Jin-Kyeung Woo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

James W Horner

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Lynda Chin

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

M Isabel Chiu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Marcus Bosenberg

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Steven C Clark

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Ronald A Depinho

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Joerg Heyer

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

publication date

20 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

71-78

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nbt.1595

15 January 2020

exact match

0 references

cites work

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

1 reference

12 December 2020

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

12 December 2020

The Catalogue of Somatic Mutations in Cancer (COSMIC)

1 reference

12 December 2020

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

12 December 2020

Essential role for oncogenic Ras in tumour maintenance

1 reference

12 December 2020

Playing only one instrument may be not enough: limitations and future of the antiangiogenic treatment of cancer.

1 reference

12 December 2020

The mighty mouse: genetically engineered mouse models in cancer drug development

1 reference

12 December 2020

Hyperplasia of mouse mammary epithelium induced by expression of the Wnt-1 (int-1) oncogene in reconstituted mammary gland

1 reference

12 December 2020

Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants

1 reference

12 December 2020

Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

1 reference

12 December 2020

Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis

1 reference

12 December 2020

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor

1 reference

12 December 2020

Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

1 reference

12 December 2020

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

1 reference

12 December 2020

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

1 reference

12 December 2020

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

1 reference

12 December 2020

Exclusive mutation in epidermal growth factor receptor gene, HER-2, and KRAS, and synchronous methylation of nonsmall cell lung cancer

1 reference

12 December 2020

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

12 December 2020

Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib

1 reference

12 December 2020

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

1 reference

12 December 2020

Multilineage hematopoietic disorders induced by transplantation of bone marrow cells expressing the v-fms oncogene

1 reference

12 December 2020

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

1 reference

12 December 2020

Scatter factor and hepatocyte growth factor: activities, properties, and mechanism

1 reference

12 December 2020

An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor.

1 reference

12 December 2020

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

1 reference

12 December 2020

Dissecting genetic requirements of human breast tumorigenesis in a tissue transgenic model of human breast cancer in mice.

1 reference

12 December 2020

Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

1 reference

12 December 2020

Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941

1 reference

12 December 2020

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.

1 reference

12 December 2020

Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials

1 reference

12 December 2020

Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

1 reference

12 December 2020

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

1 reference

12 December 2020

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

1 reference

12 December 2020

Use of avian retroviral vectors to introduce transcriptional regulators into mammalian cells for analyses of tumor maintenance

1 reference

12 December 2020

Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors

1 reference

12 December 2020

Pharmacological characterization of MP-412 (AV-412), a dual epidermal growth factor receptor and ErbB2 tyrosine kinase inhibitor

1 reference

12 December 2020

KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

1 reference

12 December 2020

The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer

1 reference

12 December 2020

Structure and clinical relevance of the epidermal growth factor receptor in human cancer

1 reference

12 December 2020

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas

1 reference

12 December 2020

Conditional gene expression in the respiratory epithelium of the mouse.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NBT.1595

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20023657%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference