The enteroinsular axis may mediate the diabetogenic effects of TCF7L2 polymorphisms (Q81359438)

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8 January 2020

title

The enteroinsular axis may mediate the diabetogenic effects of TCF7L2 polymorphisms (English)

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8 January 2020

author name string

M A Nauck

series ordinal

1

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8 January 2020

J J Meier

series ordinal

2

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8 January 2020

language of work or name

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1 December 2007

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8 January 2020

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8 January 2020

volume

50

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8 January 2020

issue

12

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8 January 2020

page(s)

2413-2416

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https://scigraph.springernature.com/pub.10.1007/s00125-007-0832-8

8 January 2020

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cites work

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TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study

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Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets

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TCF7L2 and type 2 diabetes--we WNT to know

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The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

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Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human -Cells and Adipose Tissue and Strong Association With Type 2 Diabetes

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

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12 December 2020

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

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12 December 2020

Variants of the transcription factor 7-like 2 gene (TCF7L2) are strongly associated with type 2 diabetes but not with the metabolic syndrome in the MONICA/KORA surveys

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12 December 2020

Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women.

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12 December 2020

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

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Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations

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TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

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12 December 2020

Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans

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Normalization of insulin responses to glucose by overnight infusion of glucagon-like peptide 1 (7-36) amide in patients with NIDDM.

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Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).

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TCF7L2: the biggest story in diabetes genetics since HLA?

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Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans

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Insulinotropic hormone glucagon-like peptide-I(7-37) stimulation of proinsulin gene expression and proinsulin biosynthesis in insulinoma beta TC-1 cells

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12 December 2020

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

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12 December 2020

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

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Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses

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The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

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Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients

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12 December 2020

Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells

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Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients

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The effects of glucagon-like peptide-I (GLP-I) on hormone secretion from isolated human pancreatic islets

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Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

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12 December 2020

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population

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12 December 2020

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion

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12 December 2020

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

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12 December 2020

Characterisation of beta-cell dysfunction of impaired glucose tolerance: evidence for impairment of incretin-induced insulin secretion.

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12 December 2020