Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors (Q80849382)

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4 January 2020

title

Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors (English)

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Andrew H-J Wang

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11

Chi-Huey Wong

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author name string

Yi-Ming Shao

1

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Wen-Bin Yang

2

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Hung-Pin Peng

3

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Min-Feng Hsu

4

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Tun-Hsun Kuo

6

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Po-Huang Liang

8

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Chun-Hung Lin

9

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An-Suei Yang

10

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publication date

1 September 2007

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volume

8

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page(s)

1654-1657

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issue

14

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Structural insights into SARS coronavirus proteins

4 January 2020

cites work

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12 December 2020

Substrate variants versus transition state analogues as noncovalent reversible enzyme inhibitors

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12 December 2020

Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors

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12 December 2020

Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease

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12 December 2020

The coronavirus replicase.

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12 December 2020

Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease

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12 December 2020

Mechanisms and enzymes involved in SARS coronavirus genome expression

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12 December 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

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12 December 2020

Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro

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12 December 2020

Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide.

1 reference

12 December 2020

Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo

1 reference

12 December 2020

SARS--beginning to understand a new virus

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12 December 2020

Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics.

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12 December 2020

Small molecules targeting severe acute respiratory syndrome human coronavirus

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12 December 2020

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

1 reference

12 December 2020

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics.

1 reference

12 December 2020

Progress in Anti-SARS Coronavirus Chemistry, Biology and Chemotherapy.

1 reference

12 December 2020

Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors

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12 December 2020

Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters

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12 December 2020

An efficient method for the synthesis of peptide aldehyde libraries employed in the discovery of reversible SARS coronavirus main protease (SARS-CoV Mpro) inhibitors

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12 December 2020

Design of wide-spectrum inhibitors targeting coronavirus main proteases

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12 December 2020

Identifiers

DOI

10.1002/CBIC.200700254

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4 January 2020

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