Proliferation profile of classical Hodgkin's lymphomas. Increased expression of the protein cyclin D2 in Hodgkin's and Reed-Sternberg cells (Q80538864)

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1 January 2020

title

Proliferation profile of classical Hodgkin's lymphomas. Increased expression of the protein cyclin D2 in Hodgkin's and Reed-Sternberg cells (English)

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1 January 2020

author name string

Maria Bai

1

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1 January 2020

Elena Tsanou

2

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1 January 2020

Niki John Agnantis

3

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1 January 2020

Sevasti Kamina

4

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1 January 2020

Constantina Grepi

5

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1 January 2020

Kalliopi Stefanaki

6

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1 January 2020

Dimitra Rontogianni

7

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1 January 2020

Vassiliki Galani

8

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1 January 2020

Panagiotis Kanavaros

9

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publication date

1 November 2004

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1 January 2020

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1 January 2020

volume

17

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issue

11

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1 January 2020

page(s)

1338-1345

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https://scigraph.springernature.com/pub.10.1038/modpathol.3800183

1 January 2020

exact match

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Part I: Hodgkin's lymphoma--molecular biology of Hodgkin and Reed-Sternberg cells

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DNA aneuploidy in Hodgkin's disease: a multiparameter flow cytometric analysis

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Growth vs. DNA strand breaks in Hodgkin's disease: impaired proliferative ability of Hodgkin and Reed-Sternberg cells

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Mitotic activity and nuclear DNA damage of large cells in Hodgkin's disease: comparison with the expression of p53 and bcl-2 proteins and the presence of Epstein-Barr virus.

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Cellular kinetic differences between Hodgkin's and anaplastic large cell lymphomas: relation to the expression of p34cdc2 and cyclin B-1.

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Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

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Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

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Characterization of NF-kappaB expression in Hodgkin's disease: inhibition of constitutively expressed NF-kappaB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells

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Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

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Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.

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Cell cycle deregulation in B-cell lymphomas.

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MDM2 and p21WAF1/CIP1, wild-type p53-induced proteins, are regularly expressed by Sternberg-Reed cells in Hodgkin's disease

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The mummified Hodgkin cell: cell death in Hodgkin's disease

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A study of p53 protein, proliferating cell nuclear antigen, and p21 in Hodgkin's disease at presentation and relapse

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Expressions of cyclin E, A, and B1 in Hodgkin and Reed-Sternberg cells: not suppressed by cyclin-dependent kinase inhibitor p21 expression

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Apoptosis of malignant cells in Hodgkin's disease is related to expression of the cdk inhibitor p27KIP1

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Nucleolar p14(ARF) overexpression in Reed-Sternberg cells in Hodgkin's lymphoma: absence of p14(ARF)/Hdm2 complexes is associated with expression of alternatively spliced Hdm2 transcripts

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Different incidence and pattern of p15INK4b and p16INK4a promoter region hypermethylation in Hodgkin's and CD30-Positive non-Hodgkin's lymphomas

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Hodgkin and Reed-Sternberg cells harbor alterations in the major tumor suppressor pathways and cell-cycle checkpoints: analyses using tissue microarrays

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7 January 2021

Gene expression profiling defines molecular subtypes of classical Hodgkin's disease.

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Cyclin D3 expression in normal, reactive and neoplastic tissues

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Expression of cyclin D2 and D3 in lymphoid lesions

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High-throughput tissue microarray analysis of G1-cyclin alterations in classical Hodgkin's lymphoma indicates overexpression of cyclin E1

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Low expression of p27 protein combined with altered p53 and Rb/p16 expression status is associated with increased expression of cyclin A and cyclin B1 in diffuse large B-cell lymphomas

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Unique phenotypic profile of monocytoid B cells: differences in comparison with the phenotypic profile observed in marginal zone B cells and so-called monocytoid B cell lymphoma

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Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

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Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2.

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Deregulated cyclin E induces chromosome instability

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Role for cyclin-dependent kinase 2 in mitosis exit.

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Cyclin D3 Compensates for Loss of Cyclin D2 in Mouse B-lymphocytes Activated via the Antigen Receptor and CD40

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p53 regulates a G2 checkpoint through cyclin B1

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