Cytochrome P450 3A5 genotype is associated with verapamil response in healthy subjects (Q80178773)

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29 December 2019

title

Cytochrome P450 3A5 genotype is associated with verapamil response in healthy subjects (English)

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29 December 2019

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Jin Y

1

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Wang YH

2

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Miao J

3

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Li L

4

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Kovacs RJ

5

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Marunde R

6

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Hamman MA

7

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Philips S

8

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Hilligoss J

9

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Hall SD

10

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publication date

18 April 2007

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Clinical Pharmacology & Therapeutics

29 December 2019

published in

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volume

82

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issue

5

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page(s)

579-585

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Electrophysiologic effects of dextro- and levo-verapamil on sinus node and AV node function in humans

29 December 2019

cites work

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Verapamil pharmacodynamics and disposition in young and elderly hypertensive patients. Altered electrocardiographic and hypotensive responses

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Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil

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The effect of short- and long-term administration of verapamil on the disposition of cytochrome P450 3A and P-glycoprotein substrates

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Disposition and pharmacologic effects of R/S-verapamil in patients with chronic atrial fibrillation: an investigation comparing single and multiple dosing

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

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Lipid-lowering response to statins is affected by CYP3A5 polymorphism

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Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage

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Genetic polymorphisms of CYP3A5 genes and concentration of the cyclosporine and tacrolimus

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Effects of d,l-verapamil on atrioventricular conduction in relation to its stereoselective first-pass metabolism

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Identification and functional characterization of eight CYP3A4 protein variants

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Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes

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High throughput detection of drug-metabolizing enzyme polymorphisms by allele-specific fluorogenic 5' nuclease chain reaction assay

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Human sympathetic activation by alpha2-adrenergic blockade with yohimbine: Bimodal, epistatic influence of cytochrome P450-mediated drug metabolism

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7 January 2021

A modern pharmaceutical company

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A New Statistical Method for Haplotype Reconstruction from Population Data

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7 January 2021

Variability of heart rate correction methods for the QT interval

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7 January 2021

Identifiers

DOI

10.1038/SJ.CLPT.6100208

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29 December 2019

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