The selective mGlu5 receptor antagonist MTEP, similar to NMDA receptor antagonists, induces social isolation in rats (Q79775681)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

The selective mGlu5 receptor antagonist MTEP, similar to NMDA receptor antagonists, induces social isolation in rats (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

5

Frank Sams-Dodd

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Eliza Koros

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Holger Rosenbrock

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Gerald Birk

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Carmen Weiss

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

publication date

14 June 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

published in

Neuropsychopharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

562-576

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16794564%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.npp.1301133

25 December 2019

exact match

0 references

cites work

Effects of single and repeated phencyclidine administration on the expression of metabotropic glutamate receptor subtype mRNAs in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Positive and negative symptoms in schizophrenia. A critical reappraisal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Ketamine-induced changes in rat behaviour: a possible animal model of schizophrenia. Test of predictive validity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Ketamine-induced changes in rat behaviour: A possible animal model of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

COMPARISON OF AMPHETAMINE PSYCHOSIS AND SCHIZOPHRENIA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Two distinct signaling pathways upregulate NMDA receptor responses via two distinct metabotropic glutamate receptor subtypes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Homer: a protein that selectively binds metabotropic glutamate receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Perspectives: acute phencyclidine intoxication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Pharmacology and functions of metabotropic glutamate receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Deficits in sensorimotor gating and tests of social behavior in a genetic model of reduced NMDA receptor function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Effects of 5-HT1A receptor agonists and NMDA receptor antagonists in the social interaction test and the elevated plus maze

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Animal models for the negative symptoms of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Characterisation of the actions of group I metabotropic glutamate receptor subtype selective ligands on excitatory amino acid release and sodium-dependent re-uptake in rat cerebrocortical minislices

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Natural history of schizophrenia subtypes. II. Positive and negative symptoms and long-term course

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Memantine in the treatment of senile dementia of the Alzheimer type.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Shyness, sociability, and social dysfunction in schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Dizocilpine-like discriminative stimulus effects of low-affinity uncompetitive NMDA antagonists.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Depression, negative symptoms, social stagnation and social decline in the early course of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Effect of Phencyclidine in Chronic Schizophrenics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Recent advances in the phencyclidine model of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Ionotropic and metabotropic glutamate receptor structure and pharmacology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Effects of ketamine in normal and schizophrenic volunteers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Use of composite scores (megascores) to measure deficit in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Potentiation of a metabotropic glutamatergic response following NMDA receptor activation in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Direct and indirect modulation of the N-methyl D-aspartate receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Ethological analysis of the effects of MK-801 upon aggressive male mice: similarity to chlordiazepoxide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Acute Effects of Ketamine on Memory Systems and Psychotic Symptoms in Healthy Volunteers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

1 reference

7 January 2021

Effect of AD-5423 on animal models of schizophrenia: phencyclidine-induced behavioral changes in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

The role of excitatory amino acids in experimental models of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Treatment of anxiety using fenobam (a nonbenzodiazepine) in a double-blind standard (diazepam) placebo-controlled study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

mGluR5, but not mGluR1, antagonist modifies MK-801-induced locomotor activity and deficit of prepulse inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

The mGlu5 receptor agonist CHPG stimulates striatal glutamate release: possible involvement of A2A receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Pharmacotoxic psychosis after memantine in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Memantine does not block antiaggressive effects of morphine in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

(+)-MK-801 induced social withdrawal in rats; a model for negative symptoms of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

The dopaminergic stabilizers (-)-OSU6162 and ACR16 reverse (+)-MK-801-induced social withdrawal in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Automation of the social interaction test by a video-tracking system: behavioural effects of repeated phencyclidine treatment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Effects of continuous D-amphetamine and phencyclidine administration on social behaviour, stereotyped behaviour, and locomotor activity in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

(+) MK-801 and phencyclidine induced neurotoxicity do not cause enduring behaviours resembling the positive and negative symptoms of schizophrenia in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Strategies to optimize the validity of disease models in the drug discovery process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Effects of the NMDA receptor channel blockers memantine and MRZ 2/579 on morphine withdrawal-facilitated aggression in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Metabotropic glutamate autoreceptors of the mGlu(5) subtype positively modulate neuronal glutamate release in the rat forebrain in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Functional interaction between mGlu 5 and NMDA receptors in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Social disability in schizophrenia: its development and prediction over 15 years in incidence cohorts in six European centres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021

Anxiolytic-like effects of the noncompetitive NMDA antagonist MK 801

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301133

7 January 2021