Characterization of Phase I and Phase II hepatic drug metabolism activities in a panel of human liver preparations (Q77845735)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Characterization of Phase I and Phase II hepatic drug metabolism activities in a panel of human liver preparations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

author name string

K R Iyer

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

M W Sinz

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

publication date

1 April 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

Chemico-biological Interactions

8 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

volume

118

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

page(s)

151-169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

Heterogeneity of cytochrome P450 and its toxicological significance

8 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Recent advances: the cytochrome P450 enzymes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

The human hepatic cytochromes P450 involved in drug metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Flavin-containing monooxygenases: catalytic mechanism and substrate specificities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Structure, catalytic mechanism, and evolution of the glutathione transferases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Human glutathione S-transferases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Biochemistry and molecular biology of drug-metabolizing sulfotransferase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Molecular enzymology of human liver cytosolic sulfotransferases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

UDP-glucuronosyltransferases: a family of detoxifying enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Biochemical individuality and its implications for drug and carcinogen metabolism: recent insights from acetyltransferase and cytochrome P4501A2 phenotyping and genotyping in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Methyltransferase pharmacogenetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

7 January 2021

Metabolic polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Pharmacogenetic phenotyping and genotyping. Present status and future potential.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Use of in vitro human metabolism studies in drug development. An industrial perspective

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

In vitro approaches can predict human drug metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Establishment of human tissue banks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

In vitro methods for assessing human hepatic drug metabolism: their use in drug development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Effects of freezing, thawing, and storing human liver microsomes on cytochrome P450 activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Metabolism of coumarin by rat, gerbil and human liver microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Synthesis and in vitro evaluation of two progressive series of bifunctional polyhydroxybenzamide catechol-O-methyltransferase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Assay of catechol O-methyltransferase by determination of the m- and p-O-methylated products using high-performance liquid chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Sulphation and glucuronidation of paracetamol in human liver: assay conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Thiopurine methyltransferase activity in a French population: h.p.l.c. assay conditions and effects of drugs and inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

Caffeine as a probe for human cytochromes P450: validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900007-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0009-2797(99)00007-1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359459%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference