Mechanism of allosteric regulation of the rod cGMP phosphodiesterase activity by the helical domain of transducin alpha subunit (Q77677969)

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7 December 2019

title

Mechanism of allosteric regulation of the rod cGMP phosphodiesterase activity by the helical domain of transducin alpha subunit (English)

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7 December 2019

author name string

W Liu

1

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7 December 2019

W A Clark

2

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7 December 2019

P Sharma

3

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7 December 2019

J K Northup

4

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7 December 2019

language of work or name

English

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publication date

1 December 1998

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Journal of Biological Chemistry

7 December 2019

number of pages

9

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based on heuristic

inferred from page(s)

published in

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7 December 2019

volume

273

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7 December 2019

page(s)

34284-34292

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7 December 2019

issue

51

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Structural elements of G alpha subunits that interact with G beta gamma, receptors, and effectors

7 December 2019

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Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein

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Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

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Functional and structural complexity of signal transduction via G-protein-coupled receptors

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Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

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Localization of the effector-specifying regions of Gi2alpha and Gqalpha

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Diversity of G proteins in signal transduction

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The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

21 January 2018

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Separate GTP binding and GTPase activating domains of a G alpha subunit

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GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

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Solution structure of the GTPase activating domain of alpha s.

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Human-Xenopus chimeras of Gs alpha reveal a new region important for its activation of adenylyl cyclase

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Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis

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Cyclic GMP cascade of vision

21 January 2018

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Molecular properties of the cGMP cascade of vertebrate photoreceptors

21 January 2018

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Reciprocal control of retinal rod cyclic GMP phosphodiesterase by its gamma subunit and transducin

21 January 2018

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Comparison of the phosphodiesterase inhibitory subunit interactions of frog and bovine rod outer segments

21 January 2018

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Activation of phosphodiesterase by transducin in bovine rod outer segments: characteristics of the successive binding of two transducins.

21 January 2018

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Activation of cGMP phosphodiesterase in retinal rods: mechanism of interaction with the GTP-binding protein (transducin).

21 January 2018

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Gustducin is a taste-cell-specific G protein closely related to the transducins

21 January 2018

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G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates

21 January 2018

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Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain

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Expression of G-protein alpha subunits in Escherichia coli.

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Guanine nucleotide binding characteristics of transducin: essential role of rhodopsin for rapid exchange of guanine nucleotides

21 January 2018

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cGMP phosphodiesterase of retinal rods is regulated by two inhibitory subunits

21 January 2018

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13 The meaning of scatchard and hill plots

21 January 2018

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The gamma subunit of rod cGMP-phosphodiesterase blocks the enzyme catalytic site

21 January 2018

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Interaction sites of the COOH-terminal region of the gamma subunit of cGMP phosphodiesterase with the GTP-bound alpha subunit of transducin

21 January 2018

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The carboxyl terminus of the gamma-subunit of rod cGMP phosphodiesterase contains distinct sites of interaction with the enzyme catalytic subunits and the alpha-subunit of transducin

21 January 2018

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Biochemical analysis of the transducin-phosphodiesterase interaction

21 January 2018

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21 January 2018

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21 January 2018

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The retinal specific protein RGS-r competes with the gamma subunit of cGMP phosphodiesterase for the alpha subunit of transducin and facilitates signal termination

21 January 2018

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Identification of an intramolecular interaction between small regions in type V adenylyl cyclase that influences stimulation of enzyme activity by Gsalpha

21 January 2018

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Use of resonance energy transfer to determine the proximity of the guanine nucleotide binding site of transducin relative to a conformationally-sensitive site on the gamma subunit of the cyclic GMP phosphodiesterase

21 January 2018

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Real time conformational changes in the retinal phosphodiesterase gamma subunit monitored by resonance energy transfer.

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21 January 2018

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Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.51.34284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9852093%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference