Elevations of DNA topoisomerase I in transitional cell carcinoma of the urinary bladder: correlation with DNA topoisomerase II-alpha and p53 expression (Q77340375)

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scientific article published on 01 April 1999

Language	Label	Description	Also known as
English	Elevations of DNA topoisomerase I in transitional cell carcinoma of the urinary bladder: correlation with DNA topoisomerase II-alpha and p53 expression	scientific article published on 01 April 1999

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scholarly article

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4 December 2019

Elevations of DNA topoisomerase I in transitional cell carcinoma of the urinary bladder: correlation with DNA topoisomerase II-alpha and p53 expression (English)

1 reference

Europe PubMed Central

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4 December 2019

transitional cell carcinoma

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author name string

K A Monnin

1

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4 December 2019

I B Bronstein

2

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4 December 2019

D K Gaffney

3

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4 December 2019

J A Holden

4

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publication date

1 April 1999

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number of pages

8

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Human Pathology

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4 December 2019

30

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4 December 2019

4

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4 December 2019

384-391

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4 December 2019

Topoisomerase I interacts with transcribed regions in Drosophila cells.

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Camptothecin-induced in vivo topoisomerase I cleavages in the transcriptionally active tyrosine aminotransferase gene

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7 January 2021

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A model for the mechanism of human topoisomerase I

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7 January 2021

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Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

1 reference

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Topoisomerase I inhibitors: the relevance of prolonged exposure for present clinical development

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7 January 2021

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Phase I and pharmacologic study of 9-aminocamptothecin colloidal dispersion formulation given as a 24-hour continuous infusion weekly times four every 5 weeks

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DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

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Topotecan, a new active drug in the second-line treatment of small-cell lung cancer: a phase II study in patients with refractory and sensitive disease. The European Organization for Research and Treatment of Cancer Early Clinical Studies Group and

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Topotecan, an active drug in the second-line treatment of epithelial ovarian cancer: results of a large European phase II study

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Evaluation of topotecan in resistant and relapsing multiple myeloma: a Southwest Oncology Group study

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Phase II trial of irinotecan in patients with metastatic colorectal carcinoma

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An early phase II study of CPT-11: a new derivative of camptothecin, for the treatment of leukemia and lymphoma.

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Immunohistochemical detection of DNA topoisomerase I in formalin fixed, paraffin wax embedded normal tissues and in ovarian carcinomas

1 reference

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Human DNA topoisomerase II-alpha: a new marker of cell proliferation in invasive breast cancer

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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Immunohistochemical staining for DNA topoisomerase II in non-Hodgkin's lymphomas

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Pathobiologic characteristics of hereditary breast cancer

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Invasion of the bladder by transitional cell carcinoma: its relation to histologic grade and expression of p53, MIB-1, c-erb B-2, epidermal growth factor receptor, and bcl-2

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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based on heuristic

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Accumulation of nuclear p53 and tumor progression in bladder cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0046-8177%2899%2990112-0

7 January 2021

based on heuristic

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The prognostic value of p53 nuclear overexpression and MIB-1 as a proliferative marker in transitional cell carcinoma of the bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0046-8177%2899%2990112-0

7 January 2021

based on heuristic

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Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0046-8177%2899%2990112-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0046-8177%2899%2990112-0

7 January 2021

based on heuristic

inferred from DOI database lookup

CPT-11: a new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0046-8177%2899%2990112-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer. West Japan Lung Cancer Group

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Comparison of DNA topoisomerase IIα expression in small cell and nonsmall cell carcinoma of the lung: In search of a mechanism of chemotherapeutic response

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Identifiers

10.1016/S0046-8177(99)90112-0

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10208458%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10208458%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

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