Modulation of insulin-like growth factor actions in L6A1 myoblasts by insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5: a dual role for IGFBP-5 (Q77221246)

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scientific article published on 01 October 1998

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English	Modulation of insulin-like growth factor actions in L6A1 myoblasts by insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5: a dual role for IGFBP-5	scientific article published on 01 October 1998

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3 December 2019

Modulation of insulin-like growth factor actions in L6A1 myoblasts by insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5: a dual role for IGFBP-5 (English)

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D Z Ewton

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S A Coolican

2

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S Mohan

3

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S D Chernausek

4

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J R Florini

5

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1 October 1998

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Journal of Cellular Physiology

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177

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1

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47-57

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3 December 2019

Carboxy-truncated insulin-like growth factor binding protein-5 stimulates mitogenesis in osteoblast-like cells

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Recombinant human insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced differentiation of L6A1 myoblasts

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Roles of insulin-like growth factor (IGF) receptors and IGF-binding proteins in IGF-II-induced proliferation and differentiation of L6A1 rat myoblasts

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Induction and peak gene expression of insulin-like growth factor II follow that of myogenin during differentiation of BC3H-1 muscle cells

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Characterization of an Insulin-Like Growth Factor Binding Protein (IGFBP-4) Produced by the B104 Rat Neuronal Cell Line: Chemical and Biological Properties and Differential Synthesis by Sublines*

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The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways.

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Proliferation precedes differentiation in IGF-I-stimulated myogenesis

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Effects of the somatomedins and insulin on myoblast differentiation in vitro

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IGF binding proteins-4, -5 and -6 may play specialized roles during L6 myoblast proliferation and differentiation

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The type II insulin-like growth factor (IGF) receptor has low affinity for IGF-I analogs: pleiotypic actions of IGFs on myoblasts are apparently mediated by the type I receptor

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IGF-II is more active than IGF-I in stimulating L6A1 myogenesis: greater mitogenic actions of IGF-I delay differentiation

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Insulin-like growth factor-I stimulates terminal myogenic differentiation by induction of myogenin gene expression

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Identifiers

10.1002/(SICI)1097-4652(199810)177:1<47::AID-JCP5>3.0.CO;2-E

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3 December 2019

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