Specificity of pyridinium inhibitors of the ubiquinone reduction sites in mitochondrial complex I (Q74746275)

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12 November 2019

title

Specificity of pyridinium inhibitors of the ubiquinone reduction sites in mitochondrial complex I (English)

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12 November 2019

author name string

H Miyoshi

1

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12 November 2019

J Iwata

2

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12 November 2019

K Sakamoto

3

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12 November 2019

H Furukawa

4

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12 November 2019

M Takada

5

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12 November 2019

H Iwamura

6

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T Watanabe

7

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Y Kodama

8

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12 November 2019

language of work or name

English

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publication date

1 July 1998

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Journal of Biological Chemistry

12 November 2019

published in

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12 November 2019

volume

273

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12 November 2019

issue

28

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12 November 2019

page(s)

17368-17374

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The mitochondrial electron transport and oxidative phosphorylation system

12 November 2019

cites work

1 reference

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The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains

21 January 2018

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Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase.

21 January 2018

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The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase

21 January 2018

1 reference

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Evidence that the inhibition sites of the neurotoxic amine 1-methyl-4-phenylpyridinium (MPP+) and of the respiratory chain inhibitor piericidin A are the same

21 January 2018

1 reference

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Inhibition of complex I by hydrophobic analogues of N-methyl-4-phenylpyridinium (MPP+) and the use of an ion-selective electrode to measure their accumulation by mitochondria and electron-transport particles

21 January 2018

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Energy-dependent Complex I-associated ubisemiquinones in submitochondrial particles.

21 January 2018

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The iron-sulfur clusters 2 and ubisemiquinone radicals of NADH:ubiquinone oxidoreductase are involved in energy coupling in submitochondrial particles

21 January 2018

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Action of sulfhydryl inhibitors on different forms of the respiratory chain-linked reduced nicotinamide-adenine dinucleotide dehydrogenase.

21 January 2018

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Inhibition by capsaicin of NADH-quinone oxidoreductases is correlated with the presence of energy-coupling site 1 in various organisms

21 January 2018

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Comparison of the inhibitory action of natural rotenone and its stereoisomers with various NADH-ubiquinone reductases

21 January 2018

1 reference

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Probing the ubiquinone reduction site of mitochondrial complex I using novel cationic inhibitors

21 January 2018

1 reference

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Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase

21 January 2018

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Inhibition of mitochondrial respiration by analogues of the dopaminergic neurotoxin 1-methyl-4-phenylpyridinium: structural requirements for accumulation-dependent enhanced inhibitory potency on intact mitochondria

21 January 2018

1 reference

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Characterization of the ubiquinone reduction site of mitochondrial complex I using bulky synthetic ubiquinones

21 January 2018

1 reference

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Protein-ubiquinone interaction: synthesis and biological properties of ethoxy ubiquinone derivatives

21 January 2018

1 reference

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Comparison of the structural features of ubiquinone reduction sites between glucose dehydrogenase in Escherichia coli and bovine heart mitochondrial complex I.

21 January 2018

1 reference

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Probing substrate binding site of the Escherichia coli quinol oxidases using synthetic ubiquinol analogues.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.28.17368

1 reference

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12 November 2019

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