Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention (Q74703072)

From Wikidata

Jump to navigation Jump to search

scientific article published on 01 September 2002

Language	Label	Description	Also known as
English	Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention	scientific article published on 01 September 2002

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

author name string

Peter L Pedersen

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Saroj Mathupala

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Annette Rempel

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

J F Geschwind

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Young Hee Ko

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

language of work or name

0 references

publication date

1 September 2002

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Biochimica et Biophysica Acta

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1555

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1-3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

14-20

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Oncogenic alterations of metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Prediction of survival in glioma patients by means of positron emission tomography

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexylcarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Remarkably enhanced expression of the type II hexokinase in rat hepatoma cell line AH130.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Complete amino acid sequence of the type II isozyme of rat hexokinase, deduced from the cloned cDNA: comparison with a hexokinase from novikoff ascites tumor.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

An introduction to the isoenzymes of mammalian hexokinase types I-III.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Human hexokinase: sequences of amino- and carboxyl-terminal halves are homologous

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Complete amino acid sequence of rat brain hexokinase, deduced from the cloned cDNA, and proposed structure of a mammalian hexokinase

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Complete amino acid sequence of the type III isozyme of rat hexokinase, deduced from the cloned cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Characterization of hexokinase isoenzyme types I and II in ascites tumor cells by an interaction with mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Hexokinase 'binding sites' of normal and tumoral human brain mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Kinetic characterization of hexokinase isoenzymes from glioma cells: implications for FDG imaging of human brain tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Isoenzyme pattern and subcellular localization of hexokinases in human breast cancer and nonpathological breast tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Stability of hexokinase II in vitro and in ascites tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

The role of mitochondrial hexokinase binding in the abnormal energy metabolism of tumor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Aberrant glycolytic metabolism of cancer cells: a remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for type II hexokinase

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Life (and death) in a malignant tumour

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Growth factors can influence cell growth and survival through effects on glucose metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Assignment of hexokinase types 1,2,3 (Hk1,2,3) and glucokinase (Gck) to rat chromosome band 20q11, 4q34, 17q12 and 14q21 respectively, by in situ hybridization.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Human hexokinase II: localization of the polymorphic gene to chromosome 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

A 2-cM genetic linkage map of human chromosome 7p that includes 47 loci

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Regional Mapping of Hexokinase-1 within the Short Arm of Chromosome 10

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Assignment of the hexokinase type 3 gene (HK3) to human chromosome band 5q35.3 by somatic cell hybrids and in situ hybridization.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

High resolution x-ray structure of yeast hexokinase, an allosteric protein exhibiting a non-symmetric arrangement of subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Gene Duplication in the Evolution of the Yeast Hexokinase Active Site

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Isolation and characterization of the discrete N- and C-terminal halves of rat brain hexokinase: retention of full catalytic activity in the isolated C-terminal half

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

The structure of mammalian hexokinase-1

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Functional organization of mammalian hexokinases: both N- and C-terminal halves of the rat type II isozyme possess catalytic sites

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Rat brain hexokinase: location of the allosteric regulatory site in a structural domain at the N-terminus of the enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Glucose catabolism in cancer cells. Isolation, sequence, and activity of the promoter for type II hexokinase

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Evidence that transcription of the hexokinase gene is increased in a rapidly growing rat hepatoma

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Isolation of the promoter for Type I hexokinase from rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

The human gene for the type III isozyme of hexokinase: structure, basal promoter, and evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Rat glucokinase gene: structure and regulation by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Glucose catabolism in cancer cells: regulation of the Type II hexokinase promoter by glucose and cyclic AMP.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Oxygen-regulated transcription factors and their role in pulmonary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Alterations in glucose metabolism in chick-embryo cells transformed by Rous sarcoma virus: intracellular levels of glycolytic intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Epidemiology of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Rising incidence of hepatocellular carcinoma in the United States

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

A phosphatase associated with metastasis of colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Chemoembolization of liver tumor in a rabbit model: assessment of tumor cell death with diffusion-weighted MR imaging and histologic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

Tumor Mitochondria and the Bioenergetics of Cancer Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Hexokinase: The Direct Link between Mitochondrial and Glycolytic Reactions in Rapidly Growing Cancer Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2802%2900248-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0005-2728(02)00248-7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12206885%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q74703072&oldid=1912366693"