Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism (Q74615796)

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12 November 2019

title

Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism (English)

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12 November 2019

4

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12 November 2019

author name string

R Prasad

series ordinal

1

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12 November 2019

W A Beard

series ordinal

2

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12 November 2019

P R Strauss

series ordinal

3

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12 November 2019

language of work or name

English

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publication date

1 June 1998

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Journal of Biological Chemistry

12 November 2019

published in

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12 November 2019

volume

273

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12 November 2019

page(s)

15263-15270

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12 November 2019

issue

24

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Instability and decay of the primary structure of DNA

12 November 2019

cites work

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21 January 2018

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Endonuclease IV (nfo) mutant of Escherichia coli

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The enzymology of apurinic/apyrimidinic endonucleases

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Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

21 January 2018

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Cloning and characterization of Rrp1, the gene encoding Drosophila strand transferase: carboxy-terminal homology to DNA repair endo/exonucleases.

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Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes

21 January 2018

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Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV

21 January 2018

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Enzymic release of 5'-terminal deoxyribose phosphate residues from damaged DNA in human cells

21 January 2018

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The Drosophila ribosomal protein S3 contains a DNA deoxyribophosphodiesterase (dRpase) activity.

21 January 2018

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Escherichia coli endonuclease III is not an endonuclease but a beta-elimination catalyst

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Stereochemical studies of the beta-elimination reactions at aldehydic abasic sites in DNA: endonuclease III from Escherichia coli, sodium hydroxide, and Lys-Trp-Lys

21 January 2018

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Purification and characterization of Escherichia coli formamidopyrimidine-DNA glycosylase that excises damaged 7-methylguanine from deoxyribonucleic acid

21 January 2018

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8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity

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Reconstitution of the DNA base excision-repair pathway

21 January 2018

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DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract.

21 January 2018

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Requirement of mammalian DNA polymerase-beta in base-excision repair.

21 January 2018

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Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I

21 January 2018

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The helix-hairpin-helix DNA-binding motif: a structural basis for non-sequence-specific recognition of DNA.

21 January 2018

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Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

21 January 2018

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Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction

21 January 2018

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Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5'-deoxyribose phosphate lyase activities

21 January 2018

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Substrate binding by human apurinic/apyrimidinic endonuclease indicates a Briggs-Haldane mechanism

21 January 2018

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Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

21 January 2018

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Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis

21 January 2018

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Molecular mechanism of base excision repair of uracil-containing DNA in yeast cell-free extracts

21 January 2018

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Active-site modification of mammalian DNA polymerase beta with pyridoxal 5'-phosphate: mechanism of inhibition and identification of lysine 71 in the deoxynucleoside triphosphate binding pocket

21 January 2018

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Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells

21 January 2018

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Properties of the Main Endonuclease Specific for Apurinic Sites of Escherichia coli (Endonuclease VI). Mechanism of Apurinic Site Excision from DNA

21 January 2018

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Impairment of proliferating cell nuclear antigen-dependent apurinic/apyrimidinic site repair on linear DNA.

21 January 2018

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Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid

21 January 2018

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Characterization of the tryptophan fluorescence and hydrodynamic properties of rat DNA polymerase beta

21 January 2018

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Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface

21 January 2018

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DNA polymerase beta: multiple conformational changes in the mechanism of catalysis

21 January 2018

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Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity

21 January 2018

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Observations on the pyridoxal 5'-phosphate inhibition of DNA polymerases

21 January 2018

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Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.24.15263

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9614142%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

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