10-Hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes (Q74541525)

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11 November 2019

title

10-Hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9585799%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

Dalén P

1

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11 November 2019

Dahl ML

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9585799%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Bernal Ruiz ML

3

1 reference

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11 November 2019

Nordin J

4

1 reference

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11 November 2019

Bertilsson L

5

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11 November 2019

publication date

1 April 1998

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Clinical Pharmacology & Therapeutics

11 November 2019

number of pages

9

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based on heuristic

inferred from page(s)

published in

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11 November 2019

volume

63

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11 November 2019

issue

4

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11 November 2019

page(s)

444-452

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Polymorphic hydroxylation of Debrisoquine in man.

11 November 2019

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Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

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A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin

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Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin

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Nomenclature for human CYP2D6 alleles.

7 January 2021

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Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine

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Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine

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Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population

7 January 2021

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Quick onset of severe abdominal pain after codeine in an ultrarapid metabolizer of debrisoquine

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Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population

7 January 2021

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Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population

7 January 2021

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E- and Z-10-hydroxylation of nortriptyline: relationship to polymorphic debrisoquine hydroxylation

7 January 2021

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Plasma concentrations of nortriptyline and its 10-hydroxy metabolite in depressed patients--relationship to the debrisoquine hydroxylation metabolic ratio

7 January 2021

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Pronounced inhibition of noradrenaline uptake by 10-hydroxymetabolites of nortriptyline

7 January 2021

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Weak binding of 10-hydroxymetabolites of nortriptyline to rat brain muscarinic acetylcholine receptors.

7 January 2021

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Little anticholinergic effect of E-10-hydroxynortriptyline compared with nortriptyline in healthy subjects

7 January 2021

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Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

7 January 2021

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Disposition of single oral doses of E-10-hydroxynortriptyline in healthy subjects, with some observations on pharmacodynamic effects

7 January 2021

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Stereoselective disposition of racemic E-10-hydroxynortriptyline in human beings

7 January 2021

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Enantioselective hydroxylation of nortriptyline in human liver microsomes, intestinal homogenate, and patients treated with nortriptyline

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0009-9236(98)90040-6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9585799%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference