Catalytic mechanism of aldose reductase studied by the combined potentials of quantum mechanics and molecular mechanics (Q74452354)

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10 November 2019

title

Catalytic mechanism of aldose reductase studied by the combined potentials of quantum mechanics and molecular mechanics (English)

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10 November 2019

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Y S Lee

1

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10 November 2019

M Hodoscek

series ordinal

2

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10 November 2019

B R Brooks

series ordinal

3

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10 November 2019

P F Kador

series ordinal

4

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10 November 2019

publication date

1 March 1998

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10 November 2019

published in

Biophysical Chemistry

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10 November 2019

volume

70

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10 November 2019

issue

3

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10 November 2019

page(s)

203-216

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Aldose reductase in the diabetic eye. XLIII Edward Jackson memorial lecture.

10 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

The role of aldose reductase in the development of diabetic complications

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Novel NADPH-binding domain revealed by the crystal structure of aldose reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Human aldose reductase: rate constants for a mechanism including interconversion of ternary complexes by recombinant wild-type enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Human aldose reductase: subtle effects revealed by rapid kinetic studies of the C298A mutant enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Human Aldose Reductase: pK of Tyrosine 48 Reveals the Preferred Ionization State for Catalysis and Inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Aldose reductase as a target for drug design: molecular modeling calculations on the binding of acyclic sugar substrates to the enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Structure of porcine aldehyde reductase holoenzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Mechanism of human aldehyde reductase: characterization of the active site pocket

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Refined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

1.7 .ANG. Structure of FR-1, a Fibroblast Growth Factor-Induced Member of the Aldo-Keto Reductase Family, Complexed with Coenzyme and Inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Residues affecting the catalysis and inhibition of rat lens aldose reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

General atomic and molecular electronic structure system

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Computer simulation and analysis of the reaction pathway of triosephosphate isomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

A combined quantum mechanical and molecular mechanical potential for molecular dynamics simulations

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Fluorescence spectrum of barnase: contributions of three tryptophan residues and a histidine-related pH dependence

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

Histidine-aromatic interactions in barnase. Elevation of histidine pKa and contribution to protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900115-4

7 January 2021

10.1016/S0301-4622(97)00115-4

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9546197%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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